| Reference |
|---|
Sato T, Yamaguchi A, Onishi M, Abe Y, Shiga T, Ishikawa K, et al. Comprehensive Gene Expression Analysis Using Human Induced Pluripotent Stem Cells Derived from Patients with Sleep Bruxism: A Preliminary In Vitro Study. Int J Mol Sci. 2024;25: pubmed publisher |
Hu R, Boshans L, Zhu B, Cai P, Tao Y, Youssef M, et al. Expanding GABAergic Neuronal Diversity in iPSC-Derived Disease Models. bioRxiv. 2024;: pubmed publisher |
Papandreou A, Singh N, Gianfrancesco L, Budinger D, Barwick K, Agrotis A, et al. Cardiac glycosides restore autophagy flux in an iPSC-derived neuronal model of WDR45 deficiency. bioRxiv. 2023;: pubmed publisher |
Daggubati V, Vykunta A, Choudhury A, Qadeer Z, Mirchia K, Saulnier O, et al. Hedgehog target genes regulate lipid metabolism to drive basal cell carcinoma and medulloblastoma. Res Sq. 2023;: pubmed publisher |
Ito R, Kimura A, Hirose Y, Hatano Y, Mima A, Mae S, et al. Elucidation of HHEX in pancreatic endoderm differentiation using a human iPSC differentiation model. Sci Rep. 2023;13:8659 pubmed publisher |
Karabiyik Acar x, Nozhatzadeh G, Tuncer A, Torun K xf6 se G, Hacihasano x11f lu E, Sahin F, et al. Production of parathyroid-like cells from thyroid stem cells in co-culture environment. Medicine (Baltimore). 2022;101:e32009 pubmed publisher |
Li X, Gordon P, Gaynes J, Fuller A, Ringuette R, Santiago C, et al. Lhx2 is a progenitor-intrinsic modulator of Sonic Hedgehog signaling during early retinal neurogenesis. elife. 2022;11: pubmed publisher |
Lee D, Song Y, Gug H, Lee J, Bae H, Park J. Nuclear Factor I-C Regulates Stemness Genes and Proliferation of Stem Cells in Various Mineralized Tissue through Epithelial-Mesenchymal Interactions in Dental Epithelial Stem Cells. Stem Cells Int. 2022;2022:1092184 pubmed publisher |
Fleck J, Jansen S, Wollny D, Zenk F, Seimiya M, Jain A, et al. Inferring and perturbing cell fate regulomes in human brain organoids. Nature. 2022;: pubmed publisher |
Hossain M, Hasegawa Ogawa M, Manome Y, Igarashi M, Wu C, Suzuki K, et al. Generation and characterization of motor neuron progenitors and motor neurons using metachromatic leukodystrophy-induced pluripotent stem cells. Mol Genet Metab Rep. 2022;31:100852 pubmed publisher |
Tan J, Lee B, Lim J, Ma D, Goh J, Goh S, et al. Parkinson's Disease-Specific Autoantibodies against the Neuroprotective Co-Chaperone STIP1. Cells. 2022;11: pubmed publisher |
Lo M, Sharir A, Paul M, Torosyan H, Agnew C, Li A, et al. CNPY4 inhibits the Hedgehog pathway by modulating membrane sterol lipids. Nat Commun. 2022;13:2407 pubmed publisher |
Moore A, Chinnaiya K, Kim D, Brown S, Stewart I, Robins S, et al. Loss of Function of the Neural Cell Adhesion Molecule NrCAM Regulates Differentiation, Proliferation and Neurogenesis in Early Postnatal Hypothalamic Tanycytes. Front Neurosci. 2022;16:832961 pubmed publisher |
Torz L, Niss K, Lundh S, Rekling J, Quintana C, Frazier S, et al. NPFF Decreases Activity of Human Arcuate NPY Neurons: A Study in Embryonic-Stem-Cell-Derived Model. Int J Mol Sci. 2022;23: pubmed publisher |
Capeling M, Huang S, Childs C, Wu J, Tsai Y, Wu A, et al. Suspension culture promotes serosal mesothelial development in human intestinal organoids. Cell Rep. 2022;38:110379 pubmed publisher |
Kerekes K, Trexler M, Banyai L, Patthy L. Wnt Inhibitory Factor 1 Binds to and Inhibits the Activity of Sonic Hedgehog. Cells. 2021;10: pubmed publisher |
Earley A, Burbulla L, Krainc D, Awatramani R. Identification of ASCL1 as a determinant for human iPSC-derived dopaminergic neurons. Sci Rep. 2021;11:22257 pubmed publisher |
Azatyan A, Zhang S, Darabi A, Siesjo P, Wang T, Zaphiropoulos P. Circular RNAs in Hedgehog Signaling Activation and Hedgehog-Mediated Medulloblastoma Tumors. Cancers (Basel). 2021;13: pubmed publisher |
Nakai K, Shiga T, Yasuhara R, Sarkar A, Abe Y, Nakamura S, et al. In vitro monitoring of HTR2A-positive neurons derived from human-induced pluripotent stem cells. Sci Rep. 2021;11:15437 pubmed publisher |
Fleck J, Sanchís Calleja F, He Z, Santel M, Boyle M, Camp J, et al. Resolving organoid brain region identities by mapping single-cell genomic data to reference atlases. Cell Stem Cell. 2021;28:1148-1159.e8 pubmed publisher |
Cui L, Zheng J, Zhao Q, Chen J, Liu H, Peng G, et al. Mutations of MAP1B encoding a microtubule-associated phosphoprotein cause sensorineural hearing loss. JCI Insight. 2020;5: pubmed publisher |
Goggi J, Qiu L, Liao M, Khanapur S, Jiang L, Boominathan R, et al. Dopamine transporter neuroimaging accurately assesses the maturation of dopamine neurons in a preclinical model of Parkinson's disease. Stem Cell Res Ther. 2020;11:347 pubmed publisher |
Cochrane C, Vaghjiani V, Szczepny A, Jayasekara W, González Rajal A, Kikuchi K, et al. Trp53 and Rb1 regulate autophagy and ligand-dependent Hedgehog signaling. J Clin Invest. 2020;130:4006-4018 pubmed publisher |
Yang C, Yong L, Liang C, Li Y, Ma Y, Wei F, et al. Genetic landscape and ligand-dependent activation of sonic hedgehog-Gli1 signaling in chordomas: a novel therapeutic target. Oncogene. 2020;39:4711-4727 pubmed publisher |
Ghaleh B, Thireau J, Cazorla O, Soleti R, Scheuermann V, Bize A, et al. Cardioprotective effect of sonic hedgehog ligand in pig models of ischemia reperfusion. Theranostics. 2020;10:4006-4016 pubmed publisher |
Hong C, Chen K, Wang W, Chiu J, Wu D, Chao T, et al. Insulin Resistance Promotes Parkinson's Disease through Aberrant Expression of α-Synuclein, Mitochondrial Dysfunction, and Deregulation of the Polo-Like Kinase 2 Signaling. Cells. 2020;9: pubmed publisher |
Boddy S, Romero Guevara R, Ji A, Unger C, Corns L, Marcotti W, et al. Generation of Otic Lineages from Integration-Free Human-Induced Pluripotent Stem Cells Reprogrammed by mRNAs. Stem Cells Int. 2020;2020:3692937 pubmed publisher |
Feng W, Wilkins O, Bang S, Ung M, Li J, An J, et al. CD36-Mediated Metabolic Rewiring of Breast Cancer Cells Promotes Resistance to HER2-Targeted Therapies. Cell Rep. 2019;29:3405-3420.e5 pubmed publisher |
Ferent J, Constable S, Gigante E, Yam P, Mariani L, Legue E, et al. The Ciliary Protein Arl13b Functions Outside of the Primary Cilium in Shh-Mediated Axon Guidance. Cell Rep. 2019;29:3356-3366.e3 pubmed publisher |
White C, Jayasekara W, Picard D, Chen J, Watkins D, Cain J, et al. A Sexually Dimorphic Role for STAT3 in Sonic Hedgehog Medulloblastoma. Cancers (Basel). 2019;11: pubmed publisher |
Zanin J, Verpeut J, Li Y, Shiflett M, Wang S, Santhakumar V, et al. The p75NTR Influences Cerebellar Circuit Development and Adult Behavior via Regulation of Cell Cycle Duration of Granule Cell Progenitors. J Neurosci. 2019;39:9119-9129 pubmed publisher |
Park S, Kim J, Myung S, Jung N, Choi Y, Jung S. Differentiation of Motor Neuron-Like Cells from Tonsil-Derived Mesenchymal Stem Cells and Their Possible Application to Neuromuscular Junction Formation. Int J Mol Sci. 2019;20: pubmed publisher |
Ma L, Wang Y, Hui Y, Du Y, Chen Z, Feng H, et al. WNT/NOTCH Pathway Is Essential for the Maintenance and Expansion of Human MGE Progenitors. Stem Cell Reports. 2019;12:934-949 pubmed publisher |
Riaz S, Ke Y, Wang F, Kayani M, Malik M. Influence of SHH/GLI1 axis on EMT mediated migration and invasion of breast cancer cells. Sci Rep. 2019;9:6620 pubmed publisher |
Elkouris M, Kouroupi G, Vourvoukelis A, Papagiannakis N, Kaltezioti V, Matsas R, et al. Long Non-coding RNAs Associated With Neurodegeneration-Linked Genes Are Reduced in Parkinson's Disease Patients. Front Cell Neurosci. 2019;13:58 pubmed publisher |
Ooi J, Langley S, Xu X, Utami K, Sim B, Huang Y, et al. Unbiased Profiling of Isogenic Huntington Disease hPSC-Derived CNS and Peripheral Cells Reveals Strong Cell-Type Specificity of CAG Length Effects. Cell Rep. 2019;26:2494-2508.e7 pubmed publisher |
Lang C, Campbell K, Ryan B, Carling P, Attar M, Vowles J, et al. Single-Cell Sequencing of iPSC-Dopamine Neurons Reconstructs Disease Progression and Identifies HDAC4 as a Regulator of Parkinson Cell Phenotypes. Cell Stem Cell. 2019;24:93-106.e6 pubmed publisher |
Playne R, Jones K, Connor B. Generation of dopamine neuronal-like cells from induced neural precursors derived from adult human cells by non-viral expression of lineage factors. J Stem Cells Regen Med. 2018;14:34-44 pubmed |
Tan K, Lim W, Chai C, Kukumberg M, Lim K, Goh E, et al. Sequential Application of Discrete Topographical Patterns Enhances Derivation of Functional Mesencephalic Dopaminergic Neurons from Human Induced Pluripotent Stem Cells. Sci Rep. 2018;8:9567 pubmed publisher |
Xu C, Zou C, Hussain M, Shi W, Shao Y, Jiang Z, et al. High expression of Sonic hedgehog in allergic airway epithelia contributes to goblet cell metaplasia. Mucosal Immunol. 2018;11:1306-1315 pubmed publisher |
Hu X, Lee J, Zheng X, Zhang J, Lin X, Song Y, et al. Efficient induction of functional ameloblasts from human keratinocyte stem cells. Stem Cell Res Ther. 2018;9:126 pubmed publisher |
Kim J, Lee J, Hwang H, Lee D, Park C, Jung S, et al. Wnt signal activation induces midbrain specification through direct binding of the beta-catenin/TCF4 complex to the EN1 promoter in human pluripotent stem cells. Exp Mol Med. 2018;50:24 pubmed publisher |
Chen C, Breslin M, Lan M. Sonic hedgehog signaling pathway promotes INSM1 transcription factor in neuroendocrine lung cancer. Cell Signal. 2018;46:83-91 pubmed publisher |
Ye X, Hong W, Hao B, Peng G, Huang L, Zhao Z, et al. PM2.5 promotes human bronchial smooth muscle cell migration via the sonic hedgehog signaling pathway. Respir Res. 2018;19:37 pubmed publisher |
Shall G, Menosky M, Decker S, Nethala P, Welchko R, Lévêque X, et al. Effects of Passage Number and Differentiation Protocol on the Generation of Dopaminergic Neurons from Rat Bone Marrow-Derived Mesenchymal Stem Cells. Int J Mol Sci. 2018;19: pubmed publisher |
Fink D, Sun M, Heyne G, Everson J, Chung H, Park S, et al. Coordinated d-cyclin/Foxd1 activation drives mitogenic activity of the Sonic Hedgehog signaling pathway. Cell Signal. 2018;44:1-9 pubmed publisher |
Xie S, Li G, Han C, Yu Y, Li N. RKIP reduction enhances radioresistance by activating the Shh signaling pathway in non-small-cell lung cancer. Onco Targets Ther. 2017;10:5605-5619 pubmed publisher |
Kasiri S, Shao C, Chen B, Wilson A, Yenerall P, Timmons B, et al. GLI1 Blockade Potentiates the Antitumor Activity of PI3K Antagonists in Lung Squamous Cell Carcinoma. Cancer Res. 2017;77:4448-4459 pubmed publisher |
Bergen D, Stevenson N, Skinner R, Stephens D, Hammond C. The Golgi matrix protein giantin is required for normal cilia function in zebrafish. Biol Open. 2017;6:1180-1189 pubmed publisher |
Spicer L, Schütz L, Williams J, Schreiber N, Evans J, Totty M, et al. G protein-coupled receptor 34 in ovarian granulosa cells of cattle: changes during follicular development and potential functional implications. Domest Anim Endocrinol. 2017;59:90-99 pubmed publisher |
Chanda D, Kurundkar A, Rangarajan S, Locy M, Bernard K, Sharma N, et al. Developmental Reprogramming in Mesenchymal Stromal Cells of Human Subjects with Idiopathic Pulmonary Fibrosis. Sci Rep. 2016;6:37445 pubmed publisher |
Wang X, Wei S, Zhao Y, Shi C, Liu P, Zhang C, et al. Anti-proliferation of breast cancer cells with itraconazole: Hedgehog pathway inhibition induces apoptosis and autophagic cell death. Cancer Lett. 2017;385:128-136 pubmed publisher |
Matevossian A, Resh M. Hedgehog Acyltransferase as a target in estrogen receptor positive, HER2 amplified, and tamoxifen resistant breast cancer cells. Mol Cancer. 2015;14:72 pubmed publisher |
Belgacem Y, Borodinsky L. Inversion of Sonic hedgehog action on its canonical pathway by electrical activity. Proc Natl Acad Sci U S A. 2015;112:4140-5 pubmed publisher |
Tang C, Pan Y, Luo H, Xiong W, Zhu H, Ruan H, et al. Hedgehog signaling stimulates the conversion of cholesterol to steroids. Cell Signal. 2015;27:487-97 pubmed publisher |
Hartfield E, Yamasaki Mann M, Ribeiro Fernandes H, Vowles J, James W, Cowley S, et al. Physiological characterisation of human iPS-derived dopaminergic neurons. PLoS ONE. 2014;9:e87388 pubmed publisher |
Williams E, Zhong X, Mohamed A, Li R, Liu Y, Dong Q, et al. Mutant astrocytes differentiated from Rett syndrome patients-specific iPSCs have adverse effects on wild-type neurons. Hum Mol Genet. 2014;23:2968-80 pubmed publisher |
Saito A, Kanemoto S, Zhang Y, Asada R, Hino K, Imaizumi K. Chondrocyte proliferation regulated by secreted luminal domain of ER stress transducer BBF2H7/CREB3L2. Mol Cell. 2014;53:127-39 pubmed publisher |
Chen D, Persson A, Sun Y, Salford L, Nord D, Englund E, et al. Better prognosis of patients with glioma expressing FGF2-dependent PDGFRA irrespective of morphological diagnosis. PLoS ONE. 2013;8:e61556 pubmed publisher |
Liu Y, Weick J, Liu H, Krencik R, Zhang X, Ma L, et al. Medial ganglionic eminence-like cells derived from human embryonic stem cells correct learning and memory deficits. Nat Biotechnol. 2013;31:440-7 pubmed publisher |
Cai J, Schleidt S, Pelta Heller J, Hutchings D, Cannarsa G, Iacovitti L. BMP and TGF-β pathway mediators are critical upstream regulators of Wnt signaling during midbrain dopamine differentiation in human pluripotent stem cells. Dev Biol. 2013;376:62-73 pubmed publisher |
Strand M, Wilson S, Dembinski J, Holsworth D, Khvat A, Okun I, et al. A novel synthetic smoothened antagonist transiently inhibits pancreatic adenocarcinoma xenografts in a mouse model. PLoS ONE. 2011;6:e19904 pubmed publisher |
Fabre P, Shimogori T, Charron F. Segregation of ipsilateral retinal ganglion cell axons at the optic chiasm requires the Shh receptor Boc. J Neurosci. 2010;30:266-75 pubmed publisher |
Kiprilov E, Awan A, Desprat R, Velho M, Clement C, Byskov A, et al. Human embryonic stem cells in culture possess primary cilia with hedgehog signaling machinery. J Cell Biol. 2008;180:897-904 pubmed publisher |
