Recombinant Human KIR2DL1/CD158a Fc Chimera Protein, CF | R&D Systems 1844-KR-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human KIR2DL1/CD158a Fc Chimera Protein, CF

catalog :

1844-KR-050

quantity :

50 ug

price :

456 USD

more info or order :

R&D Systems product webpage

citations: 5

Reference
Fittje P, H x153 lzemer A, Garcia Beltran W, Vollmers S, Niehrs A, Hagemann K, et al. HIV-1 Nef-mediated downregulation of CD155 results in viral restriction by KIR2DL5+ NK cells. PLoS Pathog. 2022;18:e1010572 pubmed publisher
Sim M, Rajagopalan S, Altmann D, Boyton R, Sun P, Long E. Human NK cell receptor KIR2DS4 detects a conserved bacterial epitope presented by HLA-C. Proc Natl Acad Sci U S A. 2019;: pubmed publisher
Wauquier N, Petitdemange C, Tarantino N, Maucourant C, Coomber M, Lungay V, et al. HLA-C-restricted viral epitopes are associated with an escape mechanism from KIR2DL2+ NK cells in Lassa virus infection. EBioMedicine. 2019;40:605-613 pubmed publisher
Chapel A, Garcia Beltran W, Hölzemer A, Ziegler M, Lunemann S, Martrus G, et al. Peptide-specific engagement of the activating NK cell receptor KIR2DS1. Sci Rep. 2017;7:2414 pubmed publisher
Cifaldi L, Romania P, Falco M, Lorenzi S, Meazza R, Petrini S, et al. ERAP1 regulates natural killer cell function by controlling the engagement of inhibitory receptors. Cancer Res. 2015;75:824-34 pubmed publisher

product information

brand :

R&D Systems

master code :

1844-KR

SKU :

1844-KR-050

product name :

Recombinant Human KIR2DL1/CD158a Fc Chimera Protein, CF

unit size :

50 ug

seo description :

The Recombinant Human KIR2DL1/CD158a Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Human KIR2DL1/CD158a Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.

target :

KIR2DL1/CD158a

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

dilution :

Bioactivity

purity :

>95%, by SDS-PAGE with silver staining

species :

Human

observed molecular weight :

72-80 kDa, reducing conditions

theoretical molecular weight :

51 kDa (monomer)

gene symbol :

KIR2DL1

details of functionality :

Measured by its ability to bind KG-1A human acute myelogenous leukemia cells in a flow cytometry assay. When 250 ng of Recombinant Human KIR2DL1/CD158a Fc Chimera is added to 1 x 106 KG-1A cells, 55% of the cells will bind to the protein.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

P43626

applications :

Bioactivity

source :

NS0-derived Recombinant Human KIR2DL1/CD158a Fc Chimera Protein, CF

USD :

456 USD

alt names :

CD158 antigen-like family member A, CD158a, CD158a antigen, CD158Ankat1, cl-42, killer cell immunoglobulin-like receptor 2DL1, killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1, killer Ig receptor, killer inhibitory receptor 2-2-1, KIR221, MHC class I NK cell receptor, Natural killer-associated transcript 1, NKAT, NKAT-1, NKAT1KIR-K64, p58 killer cell inhibitory receptor KIR-K64, p58 natural killer cell receptor clones CL-42/47.11, p58 NK cell inhibitory receptor NKR-K6,47.11, p58 NK receptor CL-42/47.11, p58.1, p58.1 MHC class-I-specific NK receptor

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage