Recombinant Human Chordin-Like 1 Protein | R&D Systems 1808-NR product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Chordin-Like 1 Protein

catalog :

1808-NR

quantity :

50 ug

price :

389 USD

citations: 5

Reference
Mann Z, Thiede B, Chang W, Shin J, May Simera H, Lovett M, et al. A gradient of Bmp7 specifies the tonotopic axis in the developing inner ear. Nat Commun. 2014;5:3839 pubmed publisher
Olsen O, Wader K, Misund K, Våtsveen T, Rø T, Mylin A, et al. Bone morphogenetic protein-9 suppresses growth of myeloma cells by signaling through ALK2 but is inhibited by endoglin. Blood Cancer J. 2014;4:e196 pubmed publisher
Zhang Y, Liu J, Tian X, Wong W, Chen Y, Wang L, et al. Inhibition of bone morphogenic protein 4 restores endothelial function in db/db diabetic mice. Arterioscler Thromb Vasc Biol. 2014;34:152-9 pubmed publisher
Talavera Adame D, Gupta A, Kurtovic S, Chaiboonma K, Arumugaswami V, Dafoe D. Bone morphogenetic protein-2/-4 upregulation promoted by endothelial cells in coculture enhances mouse embryoid body differentiation. Stem Cells Dev. 2013;22:3252-60 pubmed publisher
Kane R, Godson C, O Brien C. Chordin-like 1, a bone morphogenetic protein-4 antagonist, is upregulated by hypoxia in human retinal pericytes and plays a role in regulating angiogenesis. Mol Vis. 2008;14:1138-48 pubmed

product information

brand :

R&D Systems

master code :

1808-NR

SKU :

1808-NR-050

product name :

Recombinant Human Chordin-Like 1 Protein

description :

The Recombinant Human Chordin-Like 1 Protein from R&D Systems is derived from NS0. The Recombinant Human Chordin-Like 1 Protein has been validated for the following applications: Bioactivity.

target :

Chordin-like 1/CHRDL1

category :

Proteins and Enzymes

unit size :

50 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.

species :

Human

observed molecular weight :

60 kDa, reducing conditions

theoretical molecular weight :

50 kDa

gene symbol :

CHRDL1

details of functionality :

Measured by its ability to inhibit BMP-4-induced activity in MC3T3-E1 mouse preosteoblast cells. The ED50 for this effect is 0.7-3.5 µg/mL in the presence of 50 ng/mL Recombinant Human BMP-4 Recombinant Human BMP-4 (Catalog # 314-BP ) and 1 µg/mL of Recombinant Human TSG (Catalog # 6684-TG ).

endotoxin note :

<0.01 EU per 1 µg of the protein by the LAL method.

catalog number base :

1808-NR

accessionNumbers :

Q9BU40

applications :

Bioactivity

source :

Mouse myeloma cell line, NS0-derived human Chordin-like 1/CHRDL1 protein Glu22-Cys450, with a C-terminal 10-His tag

2020 USD :

369

2021 USD :

389 USD

alt names :

CHL, chordin-like 1, chordin-like protein 1, CHRDL1, CRDL1, dA141H5.1, Neuralin 1, neuralin-1, Neurogenesin-1, NRLN1, NRLN1neuralin 1, ventroptin, Ventroptin alpha, VOPT

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.