Recombinant Human Cadherin-11 (CAD-11) Fc Chimera, CF | R&D Systems 1790-CA-050 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Cadherin-11 (CAD-11) Fc Chimera, CF

catalog :

1790-CA-050

quantity :

50 ug

price :

456 USD

citations: 2

Reference
Chu K, Cheng C, Ye X, Lee Y, Zurita A, Chen D, et al. Cadherin-11 promotes the metastasis of prostate cancer cells to bone. Mol Cancer Res. 2008;6:1259-67 pubmed publisher
Pittet P, Lee K, Kulik A, Meister J, Hinz B. Fibrogenic fibroblasts increase intercellular adhesion strength by reinforcing individual OB-cadherin bonds. J Cell Sci. 2008;121:877-86 pubmed publisher

product information

master code :

1790-CA

SKU :

1790-CA-050

product name :

Recombinant Human Cadherin-11 (CAD-11) Fc Chimera, CF

unit size :

50 ug

description :

The Recombinant Human Cadherin-11 (CAD-11) Fc Chimera, CF from R&D Systems is derived from NS0. The Recombinant Human Cadherin-11 (CAD-11) Fc Chimera, CF has been validated for the following applications: Bioactivity.

target :

Cadherin-11

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in MES and NaCl with Trehalose.

conjugate :

Unconjugated

purity :

>85%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Human

observed molecular weight :

110-120 kDa, reducing conditions

theoretical molecular weight :

93 kDa (pro), 90 kDa (mature)

gene symbol :

CDH11

details of functionality :

Measured by the ability of the immobilized protein to support the adhesion of MDA-MB-231 human breast cancer cells. When 7.5 x 104 cells/well are added to Recombinant Human Cadherin-11 Fc Chimera coated plates (20 ╡g/mL with 100 ╡L/well), =50% of cells will adhere after 1 hour at 37 ░C.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

AAA35622

applications :

Bioactivity

source long :

Mouse myeloma cell line, NS0-derived human Cadherin-11 protein Human Cadherin-11 Phe-23-Thr617 (pro) Gly54-Thr617 (mature) Accession # AAA35622 DIEGRMD Human IgG1 (Pro100-Lys330) 6-His tag N-terminus C-terminus

source short :

NS0

USD :

456 USD

alt names :

CAD11OSF-4, cadherin 11, type 2, OB-cadherin (osteoblast), cadherin-11, Cadherin11, CDH11, CDHOB, OB, OB-cadherin, Osteoblast cadherin

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.