Recombinant Mouse IL-28B/IFN-lambda 3 Protein | R&D Systems 1789-ML-025 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse IL-28B/IFN-lambda 3 Protein

catalog :

1789-ML-025

quantity :

25 ug

price :

432 USD

more info or order :

R&D Systems product webpage

citations: 9

Reference
Danastas K, Guo G, Merjane J, Hong N, Larsen A, Miranda Saksena M, et al. Interferon inhibits the release of herpes simplex virus-1 from the axons of sensory neurons. MBio. 2023;14:e0181823 pubmed publisher
Won J, Jo A, Gil C, Kim S, Shin H, Jik Kim H. Inhaled delivery of recombinant interferon-lambda restores allergic inflammation after development of asthma by controlling Th2- and Th17-cell-mediated immune responses. Int Immunopharmacol. 2022;112:109180 pubmed publisher
Li Z, Wang J, Chen C, He Q, Xu X, Da Z, et al. Intratumoral IL-28B Gene Delivery Elicits Antitumor Effects by Remodeling of the Tumor Microenvironment in H22-Bearing Mice. J Immunol Res. 2022;2022:1345971 pubmed publisher
McGuire J, Frieling J, Lo C, Li T, Muhammad A, Lawrence H, et al. Mesenchymal stem cell-derived interleukin-28 drives the selection of apoptosis resistant bone metastatic prostate cancer. Nat Commun. 2021;12:723 pubmed publisher
Liou A, Liao C, Chou S, Chang Y, Chang C, Shih C. Hypoxia and therapeutic treatment of EV-A71 with an immune modulator TLR7 agonist in a new immunocompetent mouse model. J Biomed Sci. 2019;26:93 pubmed publisher
Reid E, Juleff N, Windsor M, Gubbins S, Roberts L, Morgan S, et al. Type I and III IFNs Produced by Plasmacytoid Dendritic Cells in Response to a Member of the Flaviviridae Suppress Cellular Immune Responses. J Immunol. 2016;196:4214-26 pubmed publisher
Anggakusuma -, Frentzen A, GÃ¼rlevik E, Yuan Q, Steinmann E, Ott M, et al. Control of hepatitis C virus replication in mouse liver-derived cells by MAVS-dependent production of type I and type III interferons. J Virol. 2015;89:3833-45 pubmed publisher
Kayamuro H, Yoshioka Y, Abe Y, Arita S, Katayama K, Nomura T, et al. Interleukin-1 family cytokines as mucosal vaccine adjuvants for induction of protective immunity against influenza virus. J Virol. 2010;84:12703-12 pubmed publisher
Rynda A, Maddaloni M, Ochoa RepÃ¡raz J, Callis G, Pascual D. IL-28 supplants requirement for T(reg) cells in protein sigma1-mediated protection against murine experimental autoimmune encephalomyelitis (EAE). PLoS ONE. 2010;5:e8720 pubmed publisher

product information

brand :

R&D Systems

master code :

1789-ML

SKU :

1789-ML-025

product name :

Recombinant Mouse IL-28B/IFN-lambda 3 Protein

unit size :

25 ug

seo description :

The Recombinant Mouse IL-28B/IFN-lambda 3 Protein from R&D Systems is derived from E. coli. The Recombinant Mouse IL-28B/IFN-lambda 3 Protein has been validated for the following applications: Bioactivity.

target :

IL-28B/IFN-lambda 3

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with BSA as a carrier protein.

conjugate :

Unconjugated

dilution :

Bioactivity

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Mouse

theoretical molecular weight :

19.7 kDa

gene symbol :

Ifnl3

details of functionality :

Measured in an anti-viral assay using HepG2 human hepatocellular carcinoma cells infected with encephalomyocarditis (EMC) virus. Sheppard, P. et al . (2003) Nat. Immunol. 4 :63. The ED50 for this effect is 0.800-8.00 ng/mL.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

NP_796370

applications :

Bioactivity

source :

E. coli-derived Recombinant Mouse IL-28B/IFN-lambda 3 Protein

USD :

432 USD

alt names :

interleukin-28B, IFN-lambda 3, IL28B, IL-28B, IL28C, interferon, lambda 3

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied.

more info or order :

R&D Systems product webpage