Recombinant Human MMP-16/MT3-MMP Protein, CF | R&D Systems 1785-MP-010 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human MMP-16/MT3-MMP Protein, CF

catalog :

1785-MP-010

quantity :

10 ug

price :

456 USD

more info or order :

R&D Systems product webpage

citations: 3

Reference
Yano H, Nishimiya D, Kawaguchi Y, Tamura M, Hashimoto R. Discovery of potent and specific inhibitors targeting the active site of MMP-9 from the engineered SPINK2 library. PLoS ONE. 2020;15:e0244656 pubmed publisher
Falkowski K, Bielecka E, Thøgersen I, Bocheńska O, Płaza K, Kalińska M, et al. Kallikrein-Related Peptidase 14 Activates Zymogens of Membrane Type Matrix Metalloproteinases (MT-MMPs)-A CleavEx Based Analysis. Int J Mol Sci. 2020;21: pubmed publisher
Tsuchiya S, Simmer J, Hu J, Richardson A, Yamakoshi F, Yamakoshi Y. Astacin proteases cleave dentin sialophosphoprotein (Dspp) to generate dentin phosphoprotein (Dpp). J Bone Miner Res. 2011;26:220-8 pubmed publisher

product information

master code :

1785-MP

SKU :

1785-MP-010

product name :

Recombinant Human MMP-16/MT3-MMP Protein, CF

unit size :

10 ug

description :

The Recombinant Human MMP-16/MT3-MMP Protein, CF from R&D Systems is derived from E. coli. The Recombinant Human MMP-16/MT3-MMP Protein, CF has been validated for the following applications: Enzyme Activity.

target :

MMP-16/MT3-MMP

category :

Proteins and Enzymes

buffer :

Supplied as a 0.2 ╡m filtered solution in Tris, NaCl, CaCl2, ZnCl2 and Glycerol.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Human

observed molecular weight :

29 kDa, reducing conditions

theoretical molecular weight :

31 kDa

gene symbol :

MMP16

details of functionality :

Measured by its ability to cleave a fluorogenic peptide substrate Mca-KPLGL-Dpa-AR-NH2 (Catalog # ES010 ). The specific activity is 250 pmol/min/╡g, as measured under the described conditions.

endotoxin note :

<1.0 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

P51512

applications :

Enzyme Activity

source long :

E. coli -derived human MMP-16/MT3-MMP protein Ala32-Gly291 (Ile152Asn), with a C-terminal 10-His tag

source short :

E. coli

USD :

456 USD

alt names :

chromosome 8 open reading frame 57, DKFZp761D112, EC 3.4.24, EC 3.4.24.-, EC 3.4.24.80, matrix metallopeptidase 16 (membrane-inserted), matrix metalloproteinase 16 (membrane-inserted), matrix metalloproteinase-16, Membrane-type matrix metalloproteinase 3, Membrane-type-3 matrix metalloproteinase, MMP16, MMP-16, MMPX2, MMP-X2, MT3MMP, MT3-MMP, MT3-MMPC8orf57, MT-MMP 3, MT-MMP2, MTMMP3, MT-MMP3, Putative transmembrane protein C8orf57

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 ░C as supplied. 3 months, -20 to -70 ░C under sterile conditions after opening.

more info or order :

R&D Systems product webpage