Recombinant Human Active Akt1 Protein, CF | R&D Systems 1775-KS-010 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Active Akt1 Protein, CF

catalog :

1775-KS-010

quantity :

10 ug

price :

534 USD

more info or order :

R&D Systems product webpage

citations: 4

Reference
Zhang J, Cen L, Zhang X, Tang C, Chen Y, Zhang Y, et al. MPST deficiency promotes intestinal epithelial cell apoptosis and aggravates inflammatory bowel disease via AKT. Redox Biol. 2022;56:102469 pubmed publisher
Hu L, Li X, Liu Q, Xu J, Ge H, Wang H, et al. UBE2S, a novel substrate of Akt1, associates with Ku70 and regulates DNA repair and glioblastoma multiforme resistance to chemotherapy. Oncogene. 2017;36:1145-1156 pubmed publisher
Sun Y, Kaneko S, Li X, Li X. The PI3K/Akt signal hyperactivates Eya1 via the SUMOylation pathway. Oncogene. 2015;34:2527-37 pubmed publisher
Switzer C, Ridnour L, Cheng R, Sparatore A, Del Soldato P, Moody T, et al. Dithiolethione compounds inhibit Akt signaling in human breast and lung cancer cells by increasing PP2A activity. Oncogene. 2009;28:3837-46 pubmed publisher

product information

brand :

R&D Systems

master code :

1775-KS

SKU :

1775-KS-010

product name :

Recombinant Human Active Akt1 Protein, CF

unit size :

10 ug

seo description :

The Recombinant Human Active Akt1 Protein, CF from R&D Systems is derived from Sf 9 (baculovirus). The Recombinant Human Active Akt1 Protein, CF has been validated for the following applications: Bioactivity.

target :

Akt1

category :

Proteins and Enzymes

buffer :

Supplied in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.25 mM DTT, 10 mM glutathione, 0.1 mM EDTA, 0.1 mM PMSF, 25% glycerol.

conjugate :

Unconjugated

dilution :

Bioactivity

purity :

>70%, by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie« Blue stain at 5 ╡g per lane.

species :

Human

observed molecular weight :

85 kDa

gene symbol :

AKT1

details of functionality :

The specific activity of Akt1 was determined to be 189 nmol/min/mg as per activity assay protocol.

top caption :

Recombinant Human Active Akt1 Protein SDS-PAGE

accessionNumbers :

NM_005163

applications :

Bioactivity

source :

Sf 9 (baculovirus)-derived Recombinant Human Active Akt1 Protein, CF

USD :

534 USD

alt names :

AKT, AKT serine/threonine kinase 1, AKT1m, CWS6, EC 2.7.11, EC 2.7.11.1, PKB, PKB alpha, PKBMGC99656, PRKBA, Protein kinase B, Protein Kinase B Alpha, Proto-oncogene c-Akt, RAC, rac protein kinase alpha, RAC-ALPHA, RAC-alpha serine/threonine-protein kinase, RAC-PK-alpha, RACPKB-ALPHA, Serine-Threonine Protein Kinase, v-akt murine thymoma viral oncogene homolog 1, V-Akt Murine Thymoma Viral Oncogene-Like Protein 1

storage :

This product is stable at Avoid repeated freeze-thaw cycles.

more info or order :

R&D Systems product webpage