Recombinant Rat IL-12 Protein | R&D Systems 1760-RL-010 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Rat IL-12 Protein

catalog :

1760-RL-010

quantity :

10 ug

price :

373 USD

citations: 2

Reference
Li Q, Cao Q, Wang C, Nguyen H, Wang X, Zheng G, et al. Dendritic cell-targeted CD40 DNA vaccine suppresses Th17 and ameliorates progression of experimental autoimmune glomerulonephritis. J Leukoc Biol. 2019;105:809-819 pubmed publisher
Erkens T, Goeminne N, Kegels A, Byloos M, Vinken P. Analytical performance of a commercial multiplex Luminex-based cytokine panel in the rat. J Pharmacol Toxicol Methods. 2018;91:43-49 pubmed publisher

product information

master code :

1760-RL

SKU :

1760-RL-010

product name :

Recombinant Rat IL-12 Protein

unit size :

10 ug

description :

The Recombinant Rat IL-12 Protein from R&D Systems is derived from Sf 21 (baculovirus). The Recombinant Rat IL-12 Protein has been validated for the following applications: Bioactivity.

target :

IL-12

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Rat

observed molecular weight :

42-45 kDa and 26-28 kDa, reducing conditions

theoretical molecular weight :

36.8 kDa (p40), 22.6 kDa (p35)

gene symbol :

Il12a

details of functionality :

Measured in a cell proliferation assay using PHA-activated mouse splenocytes. Mattner, F. et al . (1993) Eur. J. Immunol. 23 :2202. The ED50 for this effect is 0.025-0.25 ng/mL.

endotoxin note :

<0.1 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

NP_072133 (p40) Q9R103 (p35)

applications :

Bioactivity

source long :

Spodoptera frugiperda , Sf 21 (baculovirus)-derived rat IL-12 protein Rat IL-12 p40 (Met23 - Ser335) Accession # NP_072133 6-His tag Rat IL-12 p35 (Arg23 - Ser215) Accession # Q9R103 6-His tag N-terminus C-terminus

source short :

Sf 21 (baculovirus)

USD :

373 USD

alt names :

CLMF p35, CLMF1, Cytotoxic lymphocyte maturation factor 35 kDa subunit, IL12, IL-12 subunit p35, IL-12, subunit p35, IL12A, interleukin 12, p35, interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocytematuration factor 1, p35), interleukin-12 alpha chain, interleukin-12 subunit alpha, natural killer cell stimulatory factor 1, 35 kD subunit, NF cell stimulatory factor chain 1, NK cell stimulatory factor chain 1, NKSF1, p35

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.