Recombinant Human TACI/TNFRSF13B Fc Chimera Protein, CF | R&D Systems 174-TC-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human TACI/TNFRSF13B Fc Chimera Protein, CF

catalog :

174-TC-050

quantity :

50 ug

price :

432 USD

more info or order :

R&D Systems product webpage

citations: 3

Reference
Mulazzani M, Huber M, Borchard S, Langer S, Angele B, Schuh E, et al. APRIL and BAFF: novel biomarkers for central nervous system lymphoma. J Hematol Oncol. 2019;12:102 pubmed publisher
Isik G, Sliepen K, van Montfort T, Sanders R. Enhanced immunogenicity of HIV-1 envelope gp140 proteins fused to APRIL. PLoS ONE. 2014;9:e107683 pubmed publisher
Moreaux J, Legouffe E, Jourdan E, Quittet P, Reme T, Lugagne C, et al. BAFF and APRIL protect myeloma cells from apoptosis induced by interleukin 6 deprivation and dexamethasone. Blood. 2004;103:3148-57 pubmed

product information

brand :

R&D Systems

master code :

174-TC

SKU :

174-TC-050

product name :

Recombinant Human TACI/TNFRSF13B Fc Chimera Protein, CF

unit size :

50 ug

seo description :

The Recombinant Human TACI/TNFRSF13B Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Human TACI/TNFRSF13B Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.

target :

TACI/TNFRSF13B

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

dilution :

Bioactivity

purity :

>90%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

observed molecular weight :

51 kDa and 40 kDa, reducing conditions

theoretical molecular weight :

45.2 kDa (starts at Ser2, monomer)31.3 kDa (starts at Ser123, monomer)

gene symbol :

TNFRSF13B

details of functionality :

Measured by its ability to inhibit BAFF-mediated proliferation of anti-IgM stimulated mouse B cells. Moore,áP.A. etáal . (1999) Science 285 :260; Gross, J.A. et al . (2000) Nature 404 :995; Schneider,áP. etáal . (1999) J. Exp. Med. 189 :1747. The ED50 for this effect is 3-10áng/mL.

endotoxin note :

<1.0 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

Q53F36

applications :

Bioactivity

source :

NS0-derived Recombinant Human TACI/TNFRSF13B Fc Chimera Protein, CF

USD :

432 USD

alt names :

CD267, CD267 antigen, CVID, CVID2, FLJ39942, MGC133214, TACIMGC39952, TNFRSF13B, TNFRSF14B, Transmembrane activator and CAML interactor, tumor necrosis factor receptor 13B, tumor necrosis factor receptor superfamily member 13B, tumor necrosis factor receptor superfamily, member 13B

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage