This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
R&D Systems
product type :
protein
product name :
Recombinant Human MIS/AMH Protein
catalog :
1737-MS
quantity :
10 ug
price :
359 USD
citations: 13
Reference
Li Y, Gao D, Xu T, Adur M, Zhang L, Luo L, et al. Anti-Müllerian hormone inhibits luteinizing hormone-induced androstenedione synthesis in porcine theca cells. Theriogenology. 2020;142:421-432 pubmed publisher
Malone S, Papadakis G, Messina A, Mimouni N, Trova S, Imbernon M, et al. Defective AMH signaling disrupts GnRH neuron development and function and contributes to hypogonadotropic hypogonadism. elife. 2019;8: pubmed publisher
Tata B, Mimouni N, Barbotin A, Malone S, Loyens A, Pigny P, et al. Elevated prenatal anti-Müllerian hormone reprograms the fetus and induces polycystic ovary syndrome in adulthood. Nat Med. 2018;24:834-846 pubmed publisher
Pankhurst M, Kelley R, Sanders R, Woodcock S, Oorschot D, Batchelor N. Anti-Müllerian hormone overexpression restricts preantral ovarian follicle survival. J Endocrinol. 2018;237:153-163 pubmed publisher
Yamamoto A, Omotehara T, Miura Y, Takada T, Yoneda N, Hirano T, et al. The mechanisms underlying the effects of AMH on Müllerian duct regression in male mice. J Vet Med Sci. 2018;80:557-567 pubmed publisher
Kano M, Sosulski A, Zhang L, Saatcioglu H, Wang D, Nagykery N, et al. AMH/MIS as a contraceptive that protects the ovarian reserve during chemotherapy. Proc Natl Acad Sci U S A. 2017;114:E1688-E1697 pubmed publisher
Xu J, Bishop C, Lawson M, Park B, Xu F. Anti-Müllerian hormone promotes pre-antral follicle growth, but inhibits antral follicle maturation and dominant follicle selection in primates. Hum Reprod. 2016;31:1522-30 pubmed publisher
Signorile P, Petraglia F, Baldi A. Anti-mullerian hormone is expressed by endometriosis tissues and induces cell cycle arrest and apoptosis in endometriosis cells. J Exp Clin Cancer Res. 2014;33:46 pubmed publisher
Wilson T, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E, et al. Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors. Nature. 2012;487:505-9 pubmed publisher
Castonguay R, Werner E, Matthews R, Presman E, Mulivor A, Solban N, et al. Soluble endoglin specifically binds bone morphogenetic proteins 9 and 10 via its orphan domain, inhibits blood vessel formation, and suppresses tumor growth. J Biol Chem. 2011;286:30034-46 pubmed publisher
Nilsson E, Schindler R, Savenkova M, Skinner M. Inhibitory actions of Anti-Müllerian Hormone (AMH) on ovarian primordial follicle assembly. PLoS ONE. 2011;6:e20087 pubmed publisher
Herrera B, Inman G. A rapid and sensitive bioassay for the simultaneous measurement of multiple bone morphogenetic proteins. Identification and quantification of BMP4, BMP6 and BMP9 in bovine and human serum. BMC Cell Biol. 2009;10:20 pubmed publisher
Wang J, Dicken C, Lustbader J, Tortoriello D. Evidence for a Müllerian-inhibiting substance autocrine/paracrine system in adult human endometrium. Fertil Steril. 2009;91:1195-203 pubmed publisher
product information
brand :
R&D Systems
master code :
1737-MS
SKU :
1737-MS-010
product name :
Recombinant Human MIS/AMH Protein
description :
The Recombinant Human MIS/AMH Protein from R&D Systems is derived from E. coli. The Recombinant Human MIS/AMH Protein has been validated for the following applications: Binding Activity.
target :
MIS/AMH
category :
Proteins and Enzymes
unit size :
10 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA with BSA as a carrier protein.
conjugate :
Unconjugated
purity :
>97%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
species :
Human
theoretical molecular weight :
11.7 kDa (monomer)
gene symbol :
AMH
details of functionality :
Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human MIS/AMH at 3 µg/mL (100 µL/well) will bind Recombinant Rat MIS RII Fc Chimera (Catalog # 1618-MR) with a linear range of 1.6-100 ng/mL.
endotoxin note :
<0.01 EU per 1 µg of the protein by the LAL method.
catalog number base :
1737-MS
accessionNumbers :
Q6GTN3
applications :
Binding Activity
source :
E. coli -derived human MIS/AMH protein Ala453-Arg560
2020 USD :
359
2021 USD :
359 USD
alt names :
AMH, MIF, MIS, Muellerian hormone, muellerian-inhibiting factor, muellerian-inhibiting substance, Mullerian hormone, Mullerian inhibiting factor, Mullerian inhibiting substance
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.