product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human MIS/AMH Protein
catalog :
1737-MS-010
quantity :
10 ug
price :
456 USD
more info or order :
R&D Systems product webpage
citations: 18
Reference
Tarabeih R, Nemerovsky L, Bar Joseph H, Eldar Boock A, Elmechaly C, Ben Ami I, et al. Pigment epithelium-derived factor expression and role in follicular development. Reprod Biomed Online. 2024;49:103981 pubmed publisher
Chen M, Guo X, Zhong Y, Liu Y, Cai B, Wu R, et al. AMH inhibits androgen production in human theca cells. J Steroid Biochem Mol Biol. 2023;226:106216 pubmed publisher
Wang K, Xu F, Maylie J, Xu J. Anti-Müllerian Hormone Regulation of Synaptic Transmission in the Hippocampus Requires MAPK Signaling and Kv4.2 Potassium Channel Activity. Front Neurosci. 2021;15:772251 pubmed publisher
Zapater C, Rocha A, Molés G, Mascoli A, Ibañez S, Zanuy S, et al. Functional Activity of Recombinant Forms of Amh and Synergistic Action with Fsh in European Sea Bass Ovary. Int J Mol Sci. 2021;22: pubmed publisher
Tumurbaatar T, Kanasaki H, Tumurgan Z, Oride A, Okada H, Kyo S. Effect of anti-Müllerian hormone on the regulation of pituitary gonadotropin subunit expression: roles of kisspeptin and its receptors in gonadotroph LβT2 cells. Endocr J. 2021;68:1091-1100 pubmed publisher
Peigné M, Pigny P, Pankhurst M, Drumez E, Loyens A, Dewailly D, et al. The proportion of cleaved anti-Müllerian hormone is higher in serum but not follicular fluid of obese women independently of polycystic ovary syndrome. Reprod Biomed Online. 2020;41:1112-1121 pubmed publisher
Li Y, Gao D, Xu T, Adur M, Zhang L, Luo L, et al. Anti-Müllerian hormone inhibits luteinizing hormone-induced androstenedione synthesis in porcine theca cells. Theriogenology. 2020;142:421-432 pubmed publisher
Malone S, Papadakis G, Messina A, Mimouni N, Trova S, Imbernon M, et al. Defective AMH signaling disrupts GnRH neuron development and function and contributes to hypogonadotropic hypogonadism. elife. 2019;8: pubmed publisher
Tata B, Mimouni N, Barbotin A, Malone S, Loyens A, Pigny P, et al. Elevated prenatal anti-Müllerian hormone reprograms the fetus and induces polycystic ovary syndrome in adulthood. Nat Med. 2018;24:834-846 pubmed publisher
Pankhurst M, Kelley R, Sanders R, Woodcock S, Oorschot D, Batchelor N. Anti-Müllerian hormone overexpression restricts preantral ovarian follicle survival. J Endocrinol. 2018;237:153-163 pubmed publisher
Yamamoto A, Omotehara T, Miura Y, Takada T, Yoneda N, Hirano T, et al. The mechanisms underlying the effects of AMH on Müllerian duct regression in male mice. J Vet Med Sci. 2018;80:557-567 pubmed publisher
Xu J, Bishop C, Lawson M, Park B, Xu F. Anti-Müllerian hormone promotes pre-antral follicle growth, but inhibits antral follicle maturation and dominant follicle selection in primates. Hum Reprod. 2016;31:1522-30 pubmed publisher
Signorile P, Petraglia F, Baldi A. Anti-mullerian hormone is expressed by endometriosis tissues and induces cell cycle arrest and apoptosis in endometriosis cells. J Exp Clin Cancer Res. 2014;33:46 pubmed publisher
Wilson T, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E, et al. Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors. Nature. 2012;487:505-9 pubmed publisher
Castonguay R, Werner E, Matthews R, Presman E, Mulivor A, Solban N, et al. Soluble endoglin specifically binds bone morphogenetic proteins 9 and 10 via its orphan domain, inhibits blood vessel formation, and suppresses tumor growth. J Biol Chem. 2011;286:30034-46 pubmed publisher
Nilsson E, Schindler R, Savenkova M, Skinner M. Inhibitory actions of Anti-Müllerian Hormone (AMH) on ovarian primordial follicle assembly. PLoS ONE. 2011;6:e20087 pubmed publisher
Herrera B, Inman G. A rapid and sensitive bioassay for the simultaneous measurement of multiple bone morphogenetic proteins. Identification and quantification of BMP4, BMP6 and BMP9 in bovine and human serum. BMC Cell Biol. 2009;10:20 pubmed publisher
Wang J, Dicken C, Lustbader J, Tortoriello D. Evidence for a Müllerian-inhibiting substance autocrine/paracrine system in adult human endometrium. Fertil Steril. 2009;91:1195-203 pubmed publisher
product information
brand :
R&D Systems
master code :
1737-MS
SKU :
1737-MS-010
product name :
Recombinant Human MIS/AMH Protein
unit size :
10 ug
seo description :
The Recombinant Human MIS/AMH Protein from R&D Systems is derived from E. coli. The Recombinant Human MIS/AMH Protein has been validated for the following applications: Binding Activity.
target :
MIS/AMH
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in Acetonitrile and TFA with BSA as a carrier protein.
conjugate :
Unconjugated
dilution :
Binding Activity
purity :
>97%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.
species :
Human
theoretical molecular weight :
11.7 kDa (monomer)
gene symbol :
AMH
details of functionality :
Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human MIS/AMH at 3 ╡g/mL (100 ╡L/well) will bind Recombinant Rat MIS RII Fc Chimera (Catalog # 1618-MR) with a linear range of 1.6-100 ng/mL.
endotoxin note :
<0.01 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
Q6GTN3
applications :
Binding Activity
source :
E. coli-derived Recombinant Human MIS/AMH Protein
USD :
456 USD
alt names :
AMH, MIF, MIS, Muellerian hormone, muellerian-inhibiting factor, muellerian-inhibiting substance, Mullerian hormone, Mullerian inhibiting factor, Mullerian inhibiting substance
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.