Recombinant Human Kallikrein 4/Prostase Protein, CF | R&D Systems 1719-SE-010 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Kallikrein 4/Prostase Protein, CF

catalog :

1719-SE-010

quantity :

10 ug

price :

432 USD

more info or order :

R&D Systems product webpage

citations: 6

Reference
Chan B, Cheng I, Rozita J, Gorshteyn I, Huang Y, Shaffer I, et al. Sodium/(calcium + potassium) exchanger NCKX4 optimizes KLK4 activity in the enamel matrix microenvironment to regulate ECM modeling. Front Physiol. 2023;14:1116091 pubmed publisher
Williams R, Perez V, Mangum J, Hubbard M. Pathogenesis of Molar Hypomineralisation: Hypomineralised 6-Year Molars Contain Traces of Fetal Serum Albumin. Front Physiol. 2020;11:619 pubmed publisher
Kantyka T, Fischer J, Wu Z, Declercq W, Reiss K, Schroder J, et al. Inhibition of kallikrein-related peptidases by the serine protease inhibitor of Kazal-type 6. Peptides. 2011;32:1187-92 pubmed publisher
Sexton D, Chen T, Martik D, Kuzmic P, Kuang G, Chen J, et al. Specific inhibition of tissue kallikrein 1 with a human monoclonal antibody reveals a potential role in airway diseases. Biochem J. 2009;422:383-92 pubmed publisher
Mukai S, Fukushima T, Naka D, Tanaka H, Osada Y, Kataoka H. Activation of hepatocyte growth factor activator zymogen (pro-HGFA) by human kallikrein 1-related peptidases. FEBS J. 2008;275:1003-17 pubmed publisher
Yoon H, Laxmikanthan G, Lee J, Blaber S, Rodriguez A, Kogot J, et al. Activation profiles and regulatory cascades of the human kallikrein-related peptidases. J Biol Chem. 2007;282:31852-64 pubmed

product information

brand :

R&D Systems

master code :

1719-SE

SKU :

1719-SE-010

product name :

Recombinant Human Kallikrein 4/Prostase Protein, CF

unit size :

10 ug

seo description :

The Recombinant Human Kallikrein 4/Prostase Protein, CF from R&D Systems is derived from NS0. The Recombinant Human Kallikrein 4/Prostase Protein, CF has been validated for the following applications: Enzyme Activity.

target :

Kallikrein 4/Prostase/EMSP1

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in Tris and NaCl.

conjugate :

Unconjugated

dilution :

Enzyme Activity

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

observed molecular weight :

33 kDa, reducing conditions

theoretical molecular weight :

26 kDa

gene symbol :

KLK4

details of functionality :

Measured by its ability to cleave the fluorogenic peptide substrate Boc-VPR-AMC (Catalog # ES011 ). The specific activity is 250 pmol/min/╡g, as measured under the described conditions.

endotoxin note :

<1.0 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

NP_004908

applications :

Enzyme Activity

source :

NS0-derived Recombinant Human Kallikrein 4/Prostase Protein, CF

USD :

432 USD

alt names :

AI2A1, ARM1, EC 3.4.21, EC 3.4.21.-, EMSP, EMSP1, EMSP1MGC116827, Enamel matrix serine proteinase 1, kallikrein 4 (prostase, enamel matrix, prostate), kallikrein-4, Kallikrein-like protein 1, kallikrein-related peptidase 4, KLK4, KLK-L1MGC116828, Prostase, PRSS17enamel matrix serine protease 1, PSTSandrogen-regulated message 1, Serine protease 17

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 ░C as supplied. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage