Recombinant Human Contactin-2/TAG1 Protein, CF | R&D Systems 1714-CN-025 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Contactin-2/TAG1 Protein, CF

catalog :

1714-CN-025

quantity :

25 ug

price :

432 USD

more info or order :

R&D Systems product webpage

citations: 3

Reference
Prüss H, Schwab J, Derst C, Görtzen A, Veh R. Neurofascin as target of autoantibodies in Guillain-Barre syndrome. Brain. 2011;134:e173; author reply e174 pubmed publisher
Derfuss T, Parikh K, Velhin S, Braun M, Mathey E, Krumbholz M, et al. Contactin-2/TAG-1-directed autoimmunity is identified in multiple sclerosis patients and mediates gray matter pathology in animals. Proc Natl Acad Sci U S A. 2009;106:8302-7 pubmed publisher
Chatzopoulou E, Miguez A, Savvaki M, Levasseur G, Muzerelle A, Muriel M, et al. Structural requirement of TAG-1 for retinal ganglion cell axons and myelin in the mouse optic nerve. J Neurosci. 2008;28:7624-36 pubmed publisher

product information

master code :

1714-CN

SKU :

1714-CN-025

product name :

Recombinant Human Contactin-2/TAG1 Protein, CF

unit size :

25 ug

description :

The Recombinant Human Contactin-2/TAG1 Protein, CF from R&D Systems is derived from NS0. The Recombinant Human Contactin-2/TAG1 Protein, CF has been validated for the following applications: Bioactivity.

target :

Contactin-2/TAG1

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

observed molecular weight :

145 kDa, reducing conditions

theoretical molecular weight :

108.9 kDa

gene symbol :

CNTN2

details of functionality :

Measured by its ability to enhance neurite outgrowth of E16-E18 rat embryonic cortical neurons. Optimal neurite outgrowth was observed when neurons were plated on 96-well culture plates that had been pre-coated with 50 ╡L/well of the rhContactin-2 solution at 10-25 ╡g/mL.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

Q02246

applications :

Bioactivity

source long :

Mouse myeloma cell line, NS0-derived human Contactin-2/TAG1 protein Leu29-Asn1012, with a C-terminal 10-His tag

source short :

NS0

USD :

432 USD

alt names :

Axonal glycoprotein TAG-1, Axonin-1, axonin-1 cell adhesion molecule, AXT, CNTN2, contactin 2 (axonal), contactin 2 (transiently expressed), contactin-2, Contactin2, DKFZp781D102, FLJ37193, MGC157722, TAG1, TAG-1, TAX, TAX1, TAX-1, TAX1FLJ42746, Transient axonal glycoprotein 1, transiently-expressed axonal glycoprotein

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage