Recombinant Human C-Reactive Protein/CRP Protein | R&D Systems 1707-CR-200 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human C-Reactive Protein/CRP Protein

catalog :

1707-CR-200

quantity :

200 ug

price :

312 USD

citations: 11

Reference
Eckmair B, Gao C, Mehta A, Dutkiewicz Z, Vanbeselaere J, Cummings R, et al. Recognition of highly branched N-glycans of the porcine whipworm by the immune system. bioRxiv. 2023;: pubmed publisher
Newman S, Wilson B, Mamerow D, Wollant B, Nyein H, Rosenberg Hasson Y, et al. Extending the dynamic range of biomarker quantification through molecular equalization. Nat Commun. 2023;14:4192 pubmed publisher
Zong D, Huang B, LI Y, Lu Y, Xiang N, Guo C, et al. Chromatin accessibility landscapes of immune cells in rheumatoid arthritis nominate monocytes in disease pathogenesis. BMC Biol. 2021;19:79 pubmed publisher
Björmsjö M, Hernell O, Lonnerdal B, Berglund S. Reducing Iron Content in Infant Formula from 8 to 2 mg/L Does Not Increase the Risk of Iron Deficiency at 4 or 6 Months of Age: A Randomized Controlled Trial. Nutrients. 2020;13: pubmed publisher
Rho D, Kim S. Demonstration of a Label-Free and Low-Cost Optical Cavity-Based Biosensor Using Streptavidin and C-Reactive Protein. Biosensors (Basel). 2020;11: pubmed publisher
Henze L, Luong T, Boehme B, Masyout J, Schneider M, Brachs S, et al. Impact of C-reactive protein on osteo-/chondrogenic transdifferentiation and calcification of vascular smooth muscle cells. Aging (Albany NY). 2019;11:5445-5462 pubmed publisher
You Y, Huang X, Chen H, Lyu X, Liu H, Lan H. C-Reactive Protein Promotes Diabetic Kidney Disease in db/db Mice via the CD32b-Smad3-mTOR signaling Pathway. Sci Rep. 2016;6:26740 pubmed publisher
Liu F, Chen H, Huang X, Chung A, Zhou L, Fu P, et al. C-reactive protein promotes diabetic kidney disease in a mouse model of type 1 diabetes. Diabetologia. 2011;54:2713-23 pubmed publisher
Zhao X, Zhang M, Wang F, Zhao Y, Li J, Wang X, et al. CRP enhances soluble LOX-1 release from macrophages by activating TNF-? converting enzyme. J Lipid Res. 2011;52:923-33 pubmed publisher
Montecucco F, Steffens S, Burger F, Pelli G, Monaco C, Mach F. C-reactive protein (CRP) induces chemokine secretion via CD11b/ICAM-1 interaction in human adherent monocytes. J Leukoc Biol. 2008;84:1109-19 pubmed publisher
Zhang R, Becnel L, Li M, Chen C, Yao Q. C-reactive protein impairs human CD14+ monocyte-derived dendritic cell differentiation, maturation and function. Eur J Immunol. 2006;36:2993-3006 pubmed

product information

master code :

1707-CR

SKU :

1707-CR-200

product name :

Recombinant Human C-Reactive Protein/CRP Protein

unit size :

200 ug

description :

The Recombinant Human C-Reactive Protein/CRP Protein from R&D Systems is derived from NS0. The Recombinant Human C-Reactive Protein/CRP Protein has been validated for the following applications: Binding Activity.

target :

C-Reactive Protein/CRP

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in Tris-HCl, NaCl and CaCl2 with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>97%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.

species :

Human

observed molecular weight :

26 kDa, reducing conditions

theoretical molecular weight :

23 kDa (monomer)

gene symbol :

CRP

details of functionality :

Measured by its binding ability in a functional ELISA. Immobilized recombinant human (rh) Fc gamma RIIA at 2 ╡g/mL (100 ╡L/well) can bind rhCRP with a linear range of 0.15-10 ╡g/mL.

endotoxin note :

<0.01 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

P02741

applications :

Binding Activity

source long :

Mouse myeloma cell line, NS0-derived human C-Reactive Protein/CRP protein Phe17-Pro224

source short :

NS0

USD :

312 USD

alt names :

C-reactive protein, C-reactive protein, pentraxin-related, CRP, MGC88244, pentraxin 1, PTX1MGC149895

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.