Recombinant Human C-Reactive Protein/CRP Protein, CF | R&D Systems 1707-CR-200/CF product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human C-Reactive Protein/CRP Protein, CF

catalog :

1707-CR-200/CF

quantity :

200 ug

price :

312 USD

more info or order :

R&D Systems product webpage

citations: 9

Reference
Zong D, Huang B, LI Y, Lu Y, Xiang N, Guo C, et al. Chromatin accessibility landscapes of immune cells in rheumatoid arthritis nominate monocytes in disease pathogenesis. BMC Biol. 2021;19:79 pubmed publisher
Björmsjö M, Hernell O, Lonnerdal B, Berglund S. Reducing Iron Content in Infant Formula from 8 to 2 mg/L Does Not Increase the Risk of Iron Deficiency at 4 or 6 Months of Age: A Randomized Controlled Trial. Nutrients. 2020;13: pubmed publisher
Rho D, Kim S. Demonstration of a Label-Free and Low-Cost Optical Cavity-Based Biosensor Using Streptavidin and C-Reactive Protein. Biosensors (Basel). 2020;11: pubmed publisher
Henze L, Luong T, Boehme B, Masyout J, Schneider M, Brachs S, et al. Impact of C-reactive protein on osteo-/chondrogenic transdifferentiation and calcification of vascular smooth muscle cells. Aging (Albany NY). 2019;11:5445-5462 pubmed publisher
You Y, Huang X, Chen H, Lyu X, Liu H, Lan H. C-Reactive Protein Promotes Diabetic Kidney Disease in db/db Mice via the CD32b-Smad3-mTOR signaling Pathway. Sci Rep. 2016;6:26740 pubmed publisher
Liu F, Chen H, Huang X, Chung A, Zhou L, Fu P, et al. C-reactive protein promotes diabetic kidney disease in a mouse model of type 1 diabetes. Diabetologia. 2011;54:2713-23 pubmed publisher
Zhao X, Zhang M, Wang F, Zhao Y, Li J, Wang X, et al. CRP enhances soluble LOX-1 release from macrophages by activating TNF-? converting enzyme. J Lipid Res. 2011;52:923-33 pubmed publisher
Montecucco F, Steffens S, Burger F, Pelli G, Monaco C, Mach F. C-reactive protein (CRP) induces chemokine secretion via CD11b/ICAM-1 interaction in human adherent monocytes. J Leukoc Biol. 2008;84:1109-19 pubmed publisher
Zhang R, Becnel L, Li M, Chen C, Yao Q. C-reactive protein impairs human CD14+ monocyte-derived dendritic cell differentiation, maturation and function. Eur J Immunol. 2006;36:2993-3006 pubmed

product information

brand :

R&D Systems

master code :

1707-CR/CF

SKU :

1707-CR-200/CF

product name :

Recombinant Human C-Reactive Protein/CRP Protein, CF

unit size :

200 ug

seo description :

The Recombinant Human C-Reactive Protein/CRP Protein, CF from R&D Systems is derived from NS0. The Recombinant Human C-Reactive Protein/CRP Protein, CF has been validated for the following applications: Binding Activity.

target :

C-Reactive Protein/CRP

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in Tris-HCl, NaCl and CaCl2.

conjugate :

Unconjugated

dilution :

Binding Activity

purity :

>97%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.

species :

Human

observed molecular weight :

26 kDa, reducing conditions

theoretical molecular weight :

23 kDa (monomer)

gene symbol :

CRP

details of functionality :

Measured by its binding ability in a functional ELISA. Immobilized recombinant human (rh) Fc gamma RIIA at 2 ╡g/mL (100 ╡L/well) can bind rhCRP with a linear range of 0.15-10 ╡g/mL.

endotoxin note :

<0.01 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

P02741

applications :

Binding Activity

source :

NS0-derived Recombinant Human C-Reactive Protein/CRP Protein, CF

USD :

312 USD

alt names :

C-reactive protein, C-reactive protein, pentraxin-related, CRP, MGC88244, pentraxin 1, PTX1MGC149895

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage