Recombinant Mouse Siglec-F Fc Chimera Protein, CF | R&D Systems 1706-SF-050 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse Siglec-F Fc Chimera Protein, CF

catalog :

1706-SF-050

quantity :

50 ug

price :

456 USD

citations: 3

Reference
Pluvinage J, Haney M, Smith B, Sun J, Iram T, Bonanno L, et al. CD22 blockade restores homeostatic microglial phagocytosis in ageing brains. Nature. 2019;568:187-192 pubmed publisher
Chen G, Brown N, Wu W, Khedri Z, Yu H, Chen X, et al. Broad and direct interaction between TLR and Siglec families of pattern recognition receptors and its regulation by Neu1. elife. 2014;3:e04066 pubmed publisher
Kiwamoto T, Brummet M, Wu F, Motari M, Smith D, Schnaar R, et al. Mice deficient in the St3gal3 gene product Î±2,3 sialyltransferase (ST3Gal-III) exhibit enhanced allergic eosinophilic airway inflammation. J Allergy Clin Immunol. 2014;133:240-7.e1-3 pubmed publisher

product information

brand :

R&D Systems, a Bio-Techne brand

catalog number base :

1706-SF

SKU :

1706-SF-050

product name :

Recombinant Mouse Siglec-F Fc Chimera Protein, CF

description :

The Recombinant Mouse Siglec-F Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse Siglec-F Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.

target :

Siglec-F

unit size :

50 ug

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Mouse

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

observed molecular weight :

90-100 kDa, reducing conditions

theoretical molecular weight :

72 kDa (monomer)

gene symbol :

Siglecf

details of functionality :

Measured by the ability of the immobilized protein to support the adhesion of human red blood cells. Kelm, S. et al . (1994) Current Biology 4 :965. The ED50 for this effect is 0.5-2.5 µg/mL.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

Q920G3

applications :

Bioactivity

product keywords :

1706-SF, rmSiglec-F/Fc, mSiglec-F, carrier-free, carrier free, 17O6-SF, 1706SF, SiglecF, Siglec F, Lectin

source :

NS0-derived Recombinant Mouse Siglec-F Fc Chimera Protein, CF

USD :

447

USD 2025 :

456 USD

alt names :

SAF2, sialic acid binding Ig like lectin 8, SIGLEC-8, SIGLEC8L, SiglecF