Recombinant Mouse WISP-1/CCN4 Protein, CF | R&D Systems 1680-WS-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse WISP-1/CCN4 Protein, CF

catalog :

1680-WS-050

quantity :

50 ug

price :

432 USD

more info or order :

R&D Systems product webpage

citations: 5

Reference
Klinke D, Fernandez A, Deng W, Razazan A, Latifizadeh H, Pirkey A. Data-driven learning how oncogenic gene expression locally alters heterocellular networks. Nat Commun. 2022;13:1986 pubmed publisher
Fernandez Ruiz R, García Alamán A, Esteban Y, Mir Coll J, Serra Navarro B, Fontcuberta PiSunyer M, et al. Wisp1 is a circulating factor that stimulates proliferation of adult mouse and human beta cells. Nat Commun. 2020;11:5982 pubmed publisher
Deng W, Fernandez A, McLaughlin S, Klinke D. WNT1-inducible signaling pathway protein 1 (WISP1/CCN4) stimulates melanoma invasion and metastasis by promoting the epithelial-mesenchymal transition. J Biol Chem. 2019;294:5261-5280 pubmed publisher
Lukjanenko L, Karaz S, Stuelsatz P, Gurriaran Rodriguez U, Michaud J, Dammone G, et al. Aging Disrupts Muscle Stem Cell Function by Impairing Matricellular WISP1 Secretion from Fibro-Adipogenic Progenitors. Cell Stem Cell. 2019;24:433-446.e7 pubmed publisher
Jin S, Chen Z, Ding X, Zhao X, Jiang X, Tong Y, et al. MECHANICAL VENTILATION AUGMENTS POLY(I:C)INDUCED LUNG INJURY VIA A WISP1-INTEGRIN β3 DEPENDENT PATHWAY IN MICE. Mol Med. 2016;22:54-63 pubmed publisher

product information

brand :

R&D Systems

master code :

1680-WS

SKU :

1680-WS-050

product name :

Recombinant Mouse WISP-1/CCN4 Protein, CF

unit size :

50 ug

seo description :

The Recombinant Mouse WISP-1/CCN4 Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse WISP-1/CCN4 Protein, CF has been validated for the following applications: Bioactivity.

target :

WISP-1/CCN4

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

dilution :

Bioactivity

purity :

>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.

species :

Mouse

observed molecular weight :

65 kDa, reducing conditions

theoretical molecular weight :

39.6 kDa

gene symbol :

Wisp1

details of functionality :

Measured by its ability to inhibit the cell growth of DU145 human prostate carcinoma cells. The ED50 for this effect is 1.5 -9 ╡g/mL.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

O54775

applications :

Bioactivity

source :

NS0-derived Recombinant Mouse WISP-1/CCN4 Protein, CF

USD :

432 USD

alt names :

CCN family member 4, CCN4, CCN4WISP1tc, WISP1, WISP-1, WISP1c, WISP1i, WNT1 induced secreted protein 1, Wnt-1 inducible signaling pathway protein 1, WNT1 inducible signaling pathway protein 1, wnt-1 signaling pathway protein 1, Wnt-1-induced secreted protein, WNT1-inducible-signaling pathway protein 1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage