Recombinant Mouse ICOS Fc Chimera Protein, CF | R&D Systems 168-CS-100 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse ICOS Fc Chimera Protein, CF

catalog :

168-CS-100

quantity :

100 ug

price :

432 USD

more info or order :

R&D Systems product webpage

citations: 3

Reference
Aragoneses Fenoll L, Montes Casado M, Ojeda G, García Paredes L, Arimura Y, Yagi J, et al. Role of endocytosis and trans-endocytosis in ICOS costimulator-induced downmodulation of the ICOS Ligand. J Leukoc Biol. 2021;110:867-884 pubmed publisher
Bakkour S, Sha W. Mapping of the ICOS binding surface of murine B7h using an unbiased, cellular library of B7h mutants created by cyclical packaging rescue. J Immunol Methods. 2008;332:151-61 pubmed publisher
Arnett H, Escobar S, Gonzalez Suarez E, Budelsky A, Steffen L, Boiani N, et al. BTNL2, a butyrophilin/B7-like molecule, is a negative costimulatory molecule modulated in intestinal inflammation. J Immunol. 2007;178:1523-33 pubmed

product information

master code :

168-CS

SKU :

168-CS-100

product name :

Recombinant Mouse ICOS Fc Chimera Protein, CF

unit size :

100 ug

description :

The Recombinant Mouse ICOS Fc Chimera Protein, CF from R&D Systems is derived from Sf 21 (baculovirus). The Recombinant Mouse ICOS Fc Chimera Protein, CF has been validated for the following applications: Binding Activity.

target :

ICOS

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Mouse

observed molecular weight :

47 kDa, reducing conditions

theoretical molecular weight :

44 kDa (monomer)

gene symbol :

Icos

details of functionality :

Measured by its binding ability in a functional ELISA. Immobilized rmICOS/Fc Chimera at 1 ╡g/mL (100 ╡L/well) can bind biotinylated rhB7-H2/Fc Chimera with a linear range of 0.156-10 ng/mL. Optimal dilutions should be determined by each laboratory for each application.

endotoxin note :

<0.1 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

NP_059508

applications :

Binding Activity

source long :

Spodoptera frugiperda , Sf 21 (baculovirus)-derived mouse ICOS protein Mouse ICOS (Glu21-Leu142) Accession # NP_059508 IEGRMD Human IgG1 (Pro100-Lys330) N-terminus C-terminus

source short :

Sf 21 (baculovirus)

USD :

432 USD

alt names :

Activation-inducible lymphocyte immunomediatory molecule, AILIM, AILIMCD278, CD278, CD278 antigen, CRP-1, CVID1, inducible costimulator, inducible T-cell costimulator, inducible T-cell co-stimulator, MGC39850

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage