Recombinant Mouse OMgp Protein, CF | R&D Systems 1674-MG-025 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse OMgp Protein, CF

catalog :

1674-MG-025

quantity :

25 ug

price :

456 USD

more info or order :

R&D Systems product webpage

citations: 3

Reference
Kawakami Y, Kurihara Y, Saito Y, Fujita Y, Yamashita T, Takei K. The Soluble Form of LOTUS inhibits Nogo Receptor-Mediated Signaling by Interfering with the Interaction Between Nogo Receptor Type 1 and p75 Neurotrophin Receptor. J Neurosci. 2018;38:2589-2604 pubmed publisher
Kurihara Y, Iketani M, Ito H, Nishiyama K, Sakakibara Y, Goshima Y, et al. LOTUS suppresses axon growth inhibition by blocking interaction between Nogo receptor-1 and all four types of its ligand. Mol Cell Neurosci. 2014;61:211-8 pubmed publisher
Robak L, Venkatesh K, Lee H, Raiker S, Duan Y, Lee Osbourne J, et al. Molecular basis of the interactions of the Nogo-66 receptor and its homolog NgR2 with myelin-associated glycoprotein: development of NgROMNI-Fc, a novel antagonist of CNS myelin inhibition. J Neurosci. 2009;29:5768-83 pubmed publisher

product information

master code :

1674-MG

SKU :

1674-MG-025

product name :

Recombinant Mouse OMgp Protein, CF

unit size :

25 ug

description :

The Recombinant Mouse OMgp Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse OMgp Protein, CF has been validated for the following applications: Bioactivity.

target :

OMgp

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS and NaCl.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Mouse

observed molecular weight :

100-120 kDa, reducing conditions

theoretical molecular weight :

45.7 kDa

gene symbol :

Omg

details of functionality :

Measured by its ability to inhibit neurite outgrowth of dissociated E13 chick embryonic dorsal root ganglia (DRG) neurons. Able to significantly inhibit neurite outgrowth when immobilized as a 3 ╡L droplet containing 200 ng on a nitrocellulose-coated microplate. All experiments were done under carrier-free conditions.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

Q63912

applications :

Bioactivity

source long :

Mouse myeloma cell line, NS0-derived mouse OMgp protein Ile25-Ser420, with a C-terminal 10-His tag

source short :

NS0

USD :

456 USD

alt names :

oligodendrocyte myelin glycoprotein, OMG, OMGPoligodendrocyte-myelin glycoprotein

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage