Recombinant Human Serpin A4/Kallistatin Protein, CF | R&D Systems 1669-PI-020 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Serpin A4/Kallistatin Protein, CF

catalog :

1669-PI-020

quantity :

20 ug

price :

541 USD

more info or order :

R&D Systems product webpage

citations: 3

Reference
Mentxaka A, G xf3 mez Ambrosi J, Ram xed rez B, Rodr xed guez A, Becerril S, Neira G, et al. Netrin-1 Promotes Visceral Adipose Tissue Inflammation in Obesity and Is Associated with Insulin Resistance. Nutrients. 2022;14: pubmed publisher
Krishna S, Li J, Wang Y, Moran C, Trollope A, Huynh P, et al. Kallistatin limits abdominal aortic aneurysm by attenuating generation of reactive oxygen species and apoptosis. Sci Rep. 2021;11:17451 pubmed publisher
Memari N, Jiang W, Diamandis E, Luo L. Enzymatic properties of human kallikrein-related peptidase 12 (KLK12). Biol Chem. 2007;388:427-35 pubmed

product information

master code :

1669-PI

SKU :

1669-PI-020

product name :

Recombinant Human Serpin A4/Kallistatin Protein, CF

unit size :

20 ug

description :

The Recombinant Human Serpin A4/Kallistatin Protein, CF from R&D Systems is derived from NS0. The Recombinant Human Serpin A4/Kallistatin Protein, CF has been validated for the following applications: Inhibition Activity.

target :

Serpin A4/Kallistatin

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in MES and NaCl.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

observed molecular weight :

57 kDa and 61 kDa, reducing conditions

theoretical molecular weight :

48 kDa

gene symbol :

SERPINA4

details of functionality :

Measured by its ability to inhibit KLK1 cleavage of a fluorogenic peptide substrate, Pro-Phe-Arg-7-amido-4-methylcoumarin (PFR-AMC). The IC50 value is 40 nM, as measured under the described conditions.

endotoxin note :

<1.0 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

AAA59454

applications :

Inhibition Activity

source long :

Mouse myeloma cell line, NS0-derived human Serpin A4/Kallistatin protein Gln21-Pro427, with a C-terminal 10-His tag

source short :

NS0

USD :

541 USD

alt names :

antitrypsin), member 4, KAL, kallistatin, KLST, KSTKallikrein inhibitor, member 4, PI-4, PI4Peptidase inhibitor 4, protease inhibitor 4 (kallistatin), serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, Serpin A4, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin)

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 ░C as supplied. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage