Recombinant Human Pappalysin-2/PAPP-A2 Protein, CF | R&D Systems 1668-ZN-020 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Pappalysin-2/PAPP-A2 Protein, CF

catalog :

1668-ZN-020

quantity :

20 ug

price :

432 USD

more info or order :

R&D Systems product webpage

citations: 4

Reference
Kim H, Fu Y, Hong H, Lee S, Lee D, Kim H. Structural basis for assembly and disassembly of the IGF/IGFBP/ALS ternary complex. Nat Commun. 2022;13:4434 pubmed publisher
Chen X, Chen K, Feng Y, Ren C, Li W, Xiao J, et al. The potential role of pregnancy-associated plasma protein-A2 in angiogenesis and development of preeclampsia. Hypertens Res. 2019;42:970-980 pubmed publisher
Wang J, Qiu Q, Haider M, Bell M, Gruslin A, Christians J. Expression of pregnancy-associated plasma protein A2 during pregnancy in human and mouse. J Endocrinol. 2009;202:337-45 pubmed publisher
Nishizawa H, Pryor Koishi K, Suzuki M, Kato T, Kogo H, Sekiya T, et al. Increased levels of pregnancy-associated plasma protein-A2 in the serum of pre-eclamptic patients. Mol Hum Reprod. 2008;14:595-602 pubmed publisher

product information

brand :

R&D Systems

master code :

1668-ZN

SKU :

1668-ZN-020

product name :

Recombinant Human Pappalysin-2/PAPP-A2 Protein, CF

unit size :

20 ug

seo description :

The Recombinant Human Pappalysin-2/PAPP-A2 Protein, CF from R&D Systems is derived from NS0. The Recombinant Human Pappalysin-2/PAPP-A2 Protein, CF has been validated for the following applications: Enzyme Activity.

target :

Pappalysin-2/PAPP-A2

category :

Proteins and Enzymes

buffer :

Supplied as a 0.2 ╡m filtered solution in Tris, NaCl and CaCl2.

conjugate :

Unconjugated

dilution :

Enzyme Activity

purity :

>90%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Human

observed molecular weight :

168 kDa, reducing conditions

theoretical molecular weight :

130 kDa

gene symbol :

PAPPA2

details of functionality :

Measured by its ability to cleave IGFBP-5. Cleavage of Recombinant Human IGFBP-5 (Catalog # 875-B5 ) by Recombinant Human Pappalysin-2/PAPP-A2 is detectable by SDS-PAGE stained by Coomassie, as measured under the described conditions.

endotoxin note :

<1.0 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

Q9BXP8

applications :

Enzyme Activity

source :

NS0-derived Recombinant Human Pappalysin-2/PAPP-A2 Protein, CF

USD :

432 USD

alt names :

EC 3.4.24.-, PAPPA2, PAPP-A2, PAPP-A2pappalysin-2, pappalysin 2, Pappalysin2, PAPPE, PAPP-E, PLAC3, placenta-specific 3, pregnancy-associated plasma preproprotein-A2, Pregnancy-associated plasma protein A2, Pregnancy-associated plasma protein E1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 ░C as supplied. 3 months, -20 to -70 ░C under sterile conditions after opening.

more info or order :

R&D Systems product webpage