Recombinant Human Podocalyxin Protein, CF | R&D Systems 1658-PD-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Podocalyxin Protein, CF

catalog :

1658-PD-050

quantity :

50 ug

price :

541 USD

more info or order :

R&D Systems product webpage

citations: 4

Reference
Chongsaritsinsuk J, Rangel Angarita V, Mahoney K, Lucas T, Enny O, Katemauswa M, et al. Quantification and site-specific analysis of co-occupied N- and O-glycopeptides. bioRxiv. 2024;: pubmed publisher
Medley B, Leclaire L, Thompson N, Mahoney K, Pluvinage B, Parson M, et al. A previously uncharacterized O-glycopeptidase from Akkermansia muciniphila requires the Tn-antigen for cleavage of the peptide bond. J Biol Chem. 2022;298:102439 pubmed publisher
Shon D, Fernandez D, Riley N, Ferracane M, Bertozzi C. Structure-guided mutagenesis of a mucin-selective metalloprotease from Akkermansia muciniphila alters substrate preferences. J Biol Chem. 2022;298:101917 pubmed publisher
Malaker S, Pedram K, Ferracane M, Bensing B, Krishnan V, Pett C, et al. The mucin-selective protease StcE enables molecular and functional analysis of human cancer-associated mucins. Proc Natl Acad Sci U S A. 2019;116:7278-7287 pubmed publisher

product information

brand :

R&D Systems

master code :

1658-PD

SKU :

1658-PD-050

product name :

Recombinant Human Podocalyxin Protein, CF

unit size :

50 ug

seo description :

The Recombinant Human Podocalyxin Protein, CF from R&D Systems is derived from NS0. The Recombinant Human Podocalyxin Protein, CF has been validated for the following applications: Bioactivity.

target :

Podocalyxin

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

dilution :

Bioactivity

purity :

>95%, by SDS-PAGE with silver staining.

species :

Human

observed molecular weight :

125-165 kDa, reducing conditions

theoretical molecular weight :

43 kDa (monomer)

gene symbol :

PODXL

details of functionality :

Measured by the ability of the immobilized protein to inhibit the adhesion of CHO Chinese hamster ovary cells transfected with P-Selectin. The ED50 for this effect is 0.08-0.4 ╡g/mL.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

top caption :

Podocalyxin Inhibits Cell Adhesion to P-Selectin.

accessionNumbers :

AAB61574.1

applications :

Bioactivity

source :

NS0-derived Recombinant Human Podocalyxin Protein, CF

USD :

541 USD

alt names :

GCTM, Gp200MGC138240, PCLP, PCLP1, PCLP-1, PCLPGCTM-2 antigen, PCpodocalyxin, POD XL, podocalyxin-like, Podocalyxin-like protein 1, PODXL

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage