Recombinant Human ECE-2 Protein, CF | R&D Systems 1645-ZN-010 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human ECE-2 Protein, CF

catalog :

1645-ZN-010

quantity :

10 ug

price :

502 USD

more info or order :

R&D Systems product webpage

citations: 3

Reference
Miners J, Love S. Endothelin-converting enzymes degrade α-synuclein and are reduced in dementia with Lewy bodies. J Neurochem. 2017;141:275-286 pubmed publisher
Palmer J, Baig S, Kehoe P, Love S. Endothelin-converting enzyme-2 is increased in Alzheimer's disease and up-regulated by Abeta. Am J Pathol. 2009;175:262-70 pubmed publisher
Roosterman D, Kempkes C, Cottrell G, Padilla B, Bunnett N, Turck C, et al. Endothelin-converting enzyme-1 degrades internalized somatostatin-14. Endocrinology. 2008;149:2200-7 pubmed publisher

product information

master code :

1645-ZN

SKU :

1645-ZN-010

product name :

Recombinant Human ECE-2 Protein, CF

unit size :

10 ug

description :

The Recombinant Human ECE-2 Protein, CF from R&D Systems is derived from NS0. The Recombinant Human ECE-2 Protein, CF has been validated for the following applications: Enzyme Activity.

target :

ECE-2

category :

Proteins and Enzymes

buffer :

Supplied as a 0.2 ╡m filtered solution in Tris, NaCl and ZnCl2.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

observed molecular weight :

113 kDa, reducing conditions

theoretical molecular weight :

79 kDa

gene symbol :

ECE2

details of functionality :

Measured by its ability to cleave the fluorogenic peptide substrate, Mca-RPPGFSAFK(Dnp)-OH (Catalog # ES005 ). The specific activity is á250ápmol/min/╡g, as measured under the described conditions.

endotoxin note :

<1.0 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

EAW78275

applications :

Enzyme Activity

source long :

Mouse myeloma cell line, NS0-derived human ECE-2 protein Gly104-Trp787, with an N-terminal 10-His tag and Val

source short :

NS0

USD :

502 USD

alt names :

EC 3.4.24, EC 3.4.24.71, ECE2, ECE-2, endothelin converting enzyme 2, endothelin-converting enzyme 2, KIAA0604MGC2408, MGC17664, MGC78487

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 ░C as supplied. 3 months, -20 to -70 ░C under sterile conditions after opening.

more info or order :

R&D Systems product webpage