This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
R&D Systems
product type :
protein
product name :
Recombinant Human Thrombospondin-2 Protein, CF
catalog :
1635-T2
quantity :
50 ug
price :
339 USD
citations: 6
Reference
Inana G, Murat C, An W, Yao X, Harris I, Cao J. RPE phagocytic function declines in age-related macular degeneration and is rescued by human umbilical tissue derived cells. J Transl Med. 2018;16:63 pubmed publisher
Roudnicky F, Yoon S, Poghosyan S, Schwager S, Poyet C, Vella G, et al. Alternative transcription of a shorter, non-anti-angiogenic thrombospondin-2 variant in cancer-associated blood vessels. Oncogene. 2018;37:2573-2585 pubmed publisher
Wang S, Hu T, Wang Z, Li N, Zhou L, Liao L, et al. Macroglia-derived thrombospondin 2 regulates alterations of presynaptic proteins of retinal neurons following elevated hydrostatic pressure. PLoS ONE. 2017;12:e0185388 pubmed publisher
Chen P, Tang C, Lin L, Tsai C, Chu C, Lin T, et al. Thrombospondin-2 promotes prostate cancer bone metastasis by the up-regulation of matrix metalloproteinase-2 through down-regulating miR-376c expression. J Hematol Oncol. 2017;10:33 pubmed publisher
Hellbach N, Weise S, Vezzali R, Wahane S, Heidrich S, Roidl D, et al. Neural deletion of Tgfbr2 impairs angiogenesis through an altered secretome. Hum Mol Genet. 2014;23:6177-90 pubmed publisher
Benner E, Luciano D, Jo R, Abdi K, Paez Gonzalez P, Sheng H, et al. Protective astrogenesis from the SVZ niche after injury is controlled by Notch modulator Thbs4. Nature. 2013;497:369-73 pubmed publisher
product information
brand :
R&D Systems
master code :
1635-T2
SKU :
1635-T2-050
product name :
Recombinant Human Thrombospondin-2 Protein, CF
description :
The Recombinant Human Thrombospondin-2 Protein, CF from R&D Systems is derived from NS0. The Recombinant Human Thrombospondin-2 Protein, CF has been validated for the following applications: Bioactivity.
target :
Thrombospondin-2
category :
Proteins and Enzymes
unit size :
50 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in MES and NaCl.
conjugate :
Unconjugated
purity :
>90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
species :
Human
observed molecular weight :
170-176 kDa, reducing conditions
theoretical molecular weight :
129 kDa
gene symbol :
THBS2
details of functionality :
Measured by the ability of the immobilized protein to support the adhesion of SVEC4-10 mouse vascular endothelial cells. . The ED50 for this effect is 0.07-0.7 µg/mL. .
endotoxin note :
<1.0 EU per 1 µg of the protein by the LAL method.
catalog number base :
1635-T2
accessionNumbers :
P35442
applications :
Bioactivity
source :
Mouse myeloma cell line, NS0-derived human Thrombospondin-2 protein Gly19-Ile1172, with a C-terminal 10-His tag
2020 USD :
339
2021 USD :
339 USD
alt names :
THBS2, thrombospondin 2, Thrombospondin2, TSP-2, TSP2thrombospondin-2
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.