Recombinant Human DC-SIGNR/CD299 Fc Chimera Protein, CF | R&D Systems 162-D2-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human DC-SIGNR/CD299 Fc Chimera Protein, CF

catalog :

162-D2-050

quantity :

50 ug

price :

432 USD

more info or order :

R&D Systems product webpage

citations: 6

Reference
Zou Z, MISASI J, Sullivan N, Sun P. Overexpression of Ebola virus envelope GP1 protein. Protein Expr Purif. 2017;135:45-53 pubmed publisher
Zhang Y, Zhang Q, Zhang M, Yuan M, Wang Z, Zhang J, et al. DC - SIGNR by influencing the lncRNA HNRNPKP2 upregulates the expression of CXCR4 in gastric cancer liver metastasis. Mol Cancer. 2017;16:78 pubmed publisher
Czajkowsky D, Andersen J, Fuchs A, Wilson T, Mekhaiel D, Colonna M, et al. Developing the IVIG biomimetic, hexa-Fc, for drug and vaccine applications. Sci Rep. 2015;5:9526 pubmed publisher
Jiang Y, Zhang C, Chen K, Chen Z, Sun Z, Zhang Z, et al. The clinical significance of DC-SIGN and DC-SIGNR, which are novel markers expressed in human colon cancer. PLoS ONE. 2014;9:e114748 pubmed publisher
Nandakumar S, Kannanganat S, Dobos K, Lucas M, Spencer J, Fang S, et al. O-mannosylation of the Mycobacterium tuberculosis adhesin Apa is crucial for T cell antigenicity during infection but is expendable for protection. PLoS Pathog. 2013;9:e1003705 pubmed publisher
Johnson T, McLellan J, Graham B. Respiratory syncytial virus glycoprotein G interacts with DC-SIGN and L-SIGN to activate ERK1 and ERK2. J Virol. 2012;86:1339-47 pubmed publisher

product information

brand :

R&D Systems

master code :

162-D2

SKU :

162-D2-050

product name :

Recombinant Human DC-SIGNR/CD299 Fc Chimera Protein, CF

unit size :

50 ug

seo description :

The Recombinant Human DC-SIGNR/CD299 Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Human DC-SIGNR/CD299 Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.

target :

DC-SIGNR/CD299

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in Tris-Citrate.

conjugate :

Unconjugated

dilution :

Bioactivity

purity :

>80%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Human

observed molecular weight :

61-66 kDa, reducing conditions

theoretical molecular weight :

61.4 kDa (monomer)

gene symbol :

CLEC4M

details of functionality :

Measured by the ability of the immobilized protein to support the adhesion of ICAM-3 expressing CHO Chinese hamster ovary cells. When 5 x 104 cells/well are added to rhDC-SIGNR/Fc Chimera coated plates (5 ╡g/mL with 100 ╡L/well), approximately 40%-70% of added cells will adhere after 1 hour at room temperature. Optimal dilutions should be determined by each laboratory for each application.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

NP_001138382

applications :

Bioactivity

source :

NS0-derived Recombinant Human DC-SIGNR/CD299 Fc Chimera Protein, CF

USD :

432 USD

alt names :

CD209L, CD209L1, CD209Ldendritic cell-specific ICAM-3-grabbing nonintegrin 2, CD299, CD299 antigenMGC129964, CLEC4M, C-type lectin domain family 4, member M, DC-SIGN2, DC-SIGN2CD209 antigen-like protein 1, DCSIGNR, DC-SIGNRDC-SIGN-related protein, DCSIGNRMGC47866, Dendritic cell-specific ICAM-3-grabbing non-integrin 2, HP10347, liver/lymph node-specific ICAM-3 grabbing non-integrin, Liver/lymph node-specific ICAM-3-grabbing non-integrin, LSIGN, L-SIGN, LSIGNC-type lectin domain family 4 member M, mannose binding C-type lectin DC-SIGNR

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage