product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human Frizzled-5 Fc Chimera (CHO-expressed), CF
catalog :
1617-FZC-050
quantity :
50 ug
price :
432 USD
more info or order :
citations: 1
Reference
Wilson T, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E, et al. Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors. Nature. 2012;487:505-9 pubmed publisher
product information
brand :
R&D Systems
master code :
1617-FZC
SKU :
1617-FZC-050
product name :
Recombinant Human Frizzled-5 Fc Chimera (CHO-expressed), CF
unit size :
50 ug
seo description :
The Recombinant Human Frizzled-5 Fc Chimera (CHO-expressed), CF from R&D Systems is derived from CHO. The Recombinant Human Frizzled-5 Fc Chimera (CHO-expressed), CF has been validated for the following applications: Bioactivity.
target :
Frizzled-5
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS.
conjugate :
Unconjugated
dilution :
Bioactivity
purity :
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.
species :
Human
observed molecular weight :
60-68 kDa, reducing conditons
theoretical molecular weight :
50.1 kDa (monomer)
gene symbol :
FZD5
details of functionality :
Measured by its binding ability in a functional ELISA. In a 100 ╡L reaction mixture containing biotinylated recombinant mouse Wnt-5a at 100 ng/mL and Recombinant Human Frizzled-5 Fc Chimera dilutions, the concentration of Recombinant Human Frizzled-5 Fc Chimera that produces 50% of the maximal binding response is found to be approximately 5-20 ng/mL. Optimal concentrations should be determined by each laboratory for each application.
endotoxin note :
<0.10 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
NP_003459
applications :
Bioactivity
source :
CHO-derived Recombinant Human Frizzled-5 Fc Chimera (CHO-expressed), CF
USD :
432 USD
alt names :
C2orf31, chromosome 2 open reading frame 31, DKFZP434E2135, frizzled (Drosophila) homolog 5, frizzled homolog 5 (Drosophila), frizzled-5, Frizzled5, Frz-5, FZ-5, FZD5, FzE5, HFZ5, MGC129692, seven-transmembrane receptor frizzled-5, Wnt receptor
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.