product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse TWEAK R/TNFRSF12 Fc Chimera Protein, CF
catalog :
1610-TW-050
quantity :
50 ug
price :
432 USD
more info or order :
R&D Systems product webpage
citations: 2
Reference
Ameri H, Liu H, Liu R, Ha Y, Paulucci Holthauzen A, Hu S, et al. TWEAK/Fn14 pathway is a novel mediator of retinal neovascularization. Invest Ophthalmol Vis Sci. 2014;55:801-13 pubmed publisher
Ando T, Ichikawa J, Wako M, Hatsushika K, Watanabe Y, Sakuma M, et al. TWEAK/Fn14 interaction regulates RANTES production, BMP-2-induced differentiation, and RANKL expression in mouse osteoblastic MC3T3-E1 cells. Arthritis Res Ther. 2006;8:R146 pubmed
product information
brand :
R&D Systems
master code :
1610-TW
SKU :
1610-TW-050
product name :
Recombinant Mouse TWEAK R/TNFRSF12 Fc Chimera Protein, CF
unit size :
50 ug
seo description :
The Recombinant Mouse TWEAK R/TNFRSF12 Fc Chimera Protein, CF from R&D Systems is derived from Sf 21 (stably transfected). The Recombinant Mouse TWEAK R/TNFRSF12 Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.
target :
TWEAK R/TNFRSF12
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS.
conjugate :
Unconjugated
dilution :
Bioactivity
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
species :
Mouse
observed molecular weight :
39 kDa, reducing conditions
theoretical molecular weight :
32 kDa (monomer)
gene symbol :
Tnfrsf12a
details of functionality :
Measured by its ability to inhibit the TWEAK-dependent proliferation of HUVEC human umbilical vein endothelial cells. The ED50 for this effect is 0.5-6 ╡g/mL in the presence of 1 ╡g/mL recombinant mouse TWEAK.
endotoxin note :
<0.10 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
Q9CR75
applications :
Bioactivity
source :
Sf 21 (stably transfected)-derived Recombinant Mouse TWEAK R/TNFRSF12 Fc Chimera Protein, CF
USD :
432 USD
alt names :
CD266, CD266 antigen, FGF-inducible 14, Fibroblast growth factor-inducible immediate-early response protein 14, Fn14, FN14tumor necrosis factor receptor superfamily member 12A, TNFRSF12, TNFRSF12A, tumor necrosis factor receptor superfamily, member 12A, TweakR, Tweak-receptor, type I transmembrane protein Fn14
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.