This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
R&D Systems
product type :
protein
product name :
Recombinant Human IL-29/IFN-lambda 1 Protein
catalog :
1598-IL
quantity :
25 ug
price :
329 USD
citations: 29
Reference |
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Zickert A, Oke V, Parodis I, Svenungsson E, Sundström Y, Gunnarsson I. Interferon (IFN)-λ is a potential mediator in lupus nephritis. Lupus Sci Med. 2016;3:e000170 pubmed
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Witte K, Gruetz G, Volk H, Looman A, Asadullah K, Sterry W, et al. Despite IFN-lambda receptor expression, blood immune cells, but not keratinocytes or melanocytes, have an impaired response to type III interferons: implications for therapeutic applications of these cytokines. Genes Immun. 2009;10:702-14 pubmed publisher
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Kato A, Favoreto S, Avila P, Schleimer R. TLR3- and Th2 cytokine-dependent production of thymic stromal lymphopoietin in human airway epithelial cells. J Immunol. 2007;179:1080-7 pubmed
|
Meager A, Visvalingam K, Dilger P, Bryan D, Wadhwa M. Biological activity of interleukins-28 and -29: comparison with type I interferons. Cytokine. 2005;31:109-18 pubmed
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product information
brand :
R&D Systems
master code :
1598-IL
SKU :
1598-IL-025
product name :
Recombinant Human IL-29/IFN-lambda 1 Protein
description :
The Recombinant Human IL-29/IFN-lambda 1 Protein from R&D Systems is derived from NS0. The Recombinant Human IL-29/IFN-lambda 1 Protein has been validated for the following applications: Bioactivity.
target :
IL-29/IFN-lambda 1
category :
Proteins and Enzymes
unit size :
25 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
species :
Human
observed molecular weight :
26-35 kDa, reducing conditions
theoretical molecular weight :
21.4 kDa
gene symbol :
IFNL1
details of functionality :
Measured in an anti-viral assay using HepG2 human hepatocellular carcinoma cells infected with encephalomyocarditis (EMC) virus. Sheppard, P. et al . (2003) Nat. Immunol. 4 :63. The ED50 for this effect is 1-5 ng/mL.
endotoxin note :
<0.10 EU per 1 µg of the protein by the LAL method.
catalog number base :
1598-IL
accessionNumbers :
Q8IU54
applications :
Bioactivity
source :
Mouse myeloma cell line, NS0-derived human IL-29/IFN-lambda 1 protein Gly20-Thr200, with a C-terminal 10-His tag
2020 USD :
329
2021 USD :
329 USD
alt names :
cytokine Zcyto21, IFNL1, IFN-lambda 1, IFN-lambda-1, IL29, IL-29, interferon lambda-1, interferon, lambda 1, interleukin 29 (interferon, lambda 1), interleukin-29, ZCYTO21
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
company information

R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.
questions and comments