Recombinant Human Fc gamma RIIIB/CD16b Protein | R&D Systems 1597-FC product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Fc gamma RIIIB/CD16b Protein

catalog :

1597-FC

quantity :

50 ug

price :

349 USD

citations: 6

Reference
Blundell P, Lu D, Wilkinson M, Dell A, Haslam S, Pleass R. Insertion of N-Terminal Hinge Glycosylation Enhances Interactions of the Fc Region of Human IgG1 Monomers with Glycan-Dependent Receptors and Blocks Hemagglutination by the Influenza Virus. J Immunol. 2019;202:1595-1611 pubmed publisher
Seo N, Polozova A, Zhang M, Yates Z, Cao S, Li H, et al. Analytical and functional similarity of Amgen biosimilar ABP 215 to bevacizumab. MAbs. 2018;10:678-691 pubmed publisher
Xie J, Yamniuk A, Borowski V, Kuhn R, Susulic V, Rex Rabe S, et al. Engineering of a novel anti-CD40L domain antibody for treatment of autoimmune diseases. J Immunol. 2014;192:4083-92 pubmed publisher
Derer S, Glorius P, Schlaeth M, Lohse S, Klausz K, Muchhal U, et al. Increasing Fc?RIIa affinity of an Fc?RIII-optimized anti-EGFR antibody restores neutrophil-mediated cytotoxicity. MAbs. 2014;6:409-21 pubmed publisher
Boltz A, Piater B, Toleikis L, Guenther R, Kolmar H, Hock B. Bi-specific aptamers mediating tumor cell lysis. J Biol Chem. 2011;286:21896-905 pubmed publisher
Bergin D, Reeves E, Meleady P, Henry M, McElvaney O, Carroll T, et al. ?-1 Antitrypsin regulates human neutrophil chemotaxis induced by soluble immune complexes and IL-8. J Clin Invest. 2010;120:4236-50 pubmed publisher

product information

brand :

R&D Systems

master code :

1597-FC

SKU :

1597-FC-050

product name :

Recombinant Human Fc gamma RIIIB/CD16b Protein

description :

The Recombinant Human Fc gamma RIIIB/CD16b Protein from R&D Systems is derived from NS0. The Recombinant Human Fc gamma RIIIB/CD16b Protein has been validated for the following applications: Binding Activity.

target :

Fc gamma RIIIB/CD16b

category :

Proteins and Enzymes

unit size :

50 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.

species :

Human

observed molecular weight :

40-60 kDa, reducing conditions

theoretical molecular weight :

22.7 kDa

gene symbol :

FCGR3B

details of functionality :

Measured by its ability to bind human IgG with an estimated Kd 150 nM.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

catalog number base :

1597-FC

accessionNumbers :

O75015

applications :

Binding Activity

source :

Mouse myeloma cell line, NS0-derived human Fc gamma RIIIB/CD16b protein Thr20-Gln208, with a C-terminal 10-His tag

2020 USD :

349

2021 USD :

349 USD

alt names :

CD16, CD16b, CD16b antigen, Fc fragment of IgG, low affinity IIIb, receptor (CD16b), Fc fragment of IgG, low affinity IIIb, receptor for (CD16), FCG3, Fc-gamma receptor IIIb (CD 16), Fc-gamma RIII, Fc-gamma RIIIb, Fc-gamma RIII-beta, FCGR3, FCGR3B, FcgRIIIB, FcR-10, fcRIII, fcRIIIb, IGFR3, IgG Fc receptor III-1, low affinity immunoglobulin gamma Fc region receptor III-B

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.