Recombinant Rat EphB1 Fc Chimera Protein, CF | R&D Systems 1596-B1-200 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Rat EphB1 Fc Chimera Protein, CF

catalog :

1596-B1-200

quantity :

200 ug

price :

373 USD

more info or order :

R&D Systems product webpage

citations: 9

Reference
Liu L, Jiang Y, Al Shabrawey M, Ren X, Wang S, Steinle J. EphB1 causes retinal damage through inflammatory pathways in the retina and retinal Müller cells. Mol Vis. 2024;30:167-174 pubmed
Grandi A, Zini I, Palese S, Giorgio C, Tognolini M, Marchesani F, et al. Targeting the Eph/Ephrin System as Anti-Inflammatory Strategy in IBD. Front Pharmacol. 2019;10:691 pubmed publisher
Tyzack G, Hall C, Sibley C, Cymes T, Forostyak S, Carlino G, et al. A neuroprotective astrocyte state is induced by neuronal signal EphB1 but fails in ALS models. Nat Commun. 2017;8:1164 pubmed publisher
Choi T, Yun M, Lee J, Park J, Park M, Kim H. Proteomic Analysis of a Rat Cerebral Ischemic Injury Model after Human Cerebral Endothelial Cell Transplantation. J Korean Neurosurg Soc. 2016;59:544-550 pubmed
Zhang G, Brady J, Liang W, Wu Y, Henkemeyer M, Yan M. EphB4 forward signalling regulates lymphatic valve development. Nat Commun. 2015;6:6625 pubmed publisher
Yu L, Zhou X, Yu J, Huang H, Jiang L, Zhang F, et al. PI3K contributed to modulation of spinal nociceptive information related to ephrinBs/EphBs. PLoS ONE. 2012;7:e40930 pubmed publisher
Slack S, Battaglia A, Cibert Goton V, Gavazzi I. EphrinB2 induces tyrosine phosphorylation of NR2B via Src-family kinases during inflammatory hyperalgesia. Neuroscience. 2008;156:175-83 pubmed publisher
Parker M, Roberts R, Enriquez M, Zhao X, Takahashi T, Pat Cerretti D, et al. Reverse endocytosis of transmembrane ephrin-B ligands via a clathrin-mediated pathway. Biochem Biophys Res Commun. 2004;323:17-23 pubmed
Dobrzanski P, Hunter K, Jones Bolin S, Chang H, Robinson C, Pritchard S, et al. Antiangiogenic and antitumor efficacy of EphA2 receptor antagonist. Cancer Res. 2004;64:910-9 pubmed

product information

brand :

R&D Systems

master code :

1596-B1

SKU :

1596-B1-200

product name :

Recombinant Rat EphB1 Fc Chimera Protein, CF

unit size :

200 ug

seo description :

The Recombinant Rat EphB1 Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Rat EphB1 Fc Chimera Protein, CF has been validated for the following applications: Binding Activity.

target :

EphB1

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in Tris.

conjugate :

Unconjugated

dilution :

Binding Activity

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Rat

observed molecular weight :

102 kDa, reducing conditions

theoretical molecular weight :

85 kDa (monomer)

gene symbol :

Ephb1

details of functionality :

Measured by its binding ability in a functional ELISA. Immobilized Recombinant Rat EphB1 Fc Chimera at 2 ╡g/mL (100 ╡L/well) can bind recombinant mouse Ephrin-B1 Fc Chimera with a linear range of 0.31-20 ng/mL. Optimal dilutions should be determined by each laboratory for each application.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

P09759

applications :

Binding Activity

source :

NS0-derived Recombinant Rat EphB1 Fc Chimera Protein, CF

USD :

373 USD

alt names :

Cek6, EC 2.7.10, EC 2.7.10.1, EK6, Elk, EPH receptor B1, eph tyrosine kinase 2, EphB1, EPH-like kinase 6, ephrin type-B receptor 1, EPHT2FLJ37986, hEK6, Net, NETHek6, soluble EPHB1 variant 1, Tyrosine-protein kinase receptor EPH-2

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage