Recombinant Mouse IGFBP-1 Protein, CF | R&D Systems 1588-B1-025 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse IGFBP-1 Protein, CF

catalog :

1588-B1-025

quantity :

25 ug

price :

432 USD

more info or order :

R&D Systems product webpage

citations: 3

Reference
Lu J, Liu K, Schulz N, Karampelias C, Charbord J, Hilding A, et al. IGFBP1 increases ?-cell regeneration by promoting ?- to ?-cell transdifferentiation. EMBO J. 2016;35:2026-44 pubmed publisher
Williams N, Interlichia J, Jackson M, Hwang D, Cohen P, Rodgers B. Endocrine actions of myostatin: systemic regulation of the IGF and IGF binding protein axis. Endocrinology. 2011;152:172-80 pubmed publisher
Yamada P, Mehta H, Hwang D, Roos K, Hevener A, Lee K. Evidence of a role for insulin-like growth factor binding protein (IGFBP)-3 in metabolic regulation. Endocrinology. 2010;151:5741-50 pubmed publisher

product information

brand :

R&D Systems

master code :

1588-B1

SKU :

1588-B1-025

product name :

Recombinant Mouse IGFBP-1 Protein, CF

unit size :

25 ug

seo description :

The Recombinant Mouse IGFBP-1 Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse IGFBP-1 Protein, CF has been validated for the following applications: Bioactivity.

target :

IGFBP-1

category :

Proteins and Enzymes

buffer :

Supplied as a 0.2 ╡m filtered solution in Acetonitrile and TFA.

conjugate :

Unconjugated

dilution :

Bioactivity

purity :

>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.

species :

Mouse

observed molecular weight :

34 kDa, reducing conditions

theoretical molecular weight :

27 kDa

gene symbol :

Igfbp1

details of functionality :

Measured by its ability to inhibit the biological activity of IGF-I or IGF-II on MCF-7 human breast cancer cells. Karey, K.P. et al . (1988) Cancer Research 48 :4083. The ED50 for this effect is typically 0.25-1.5 ╡g/mL in the presence of 2.5 ng/mL Recombinant Mouse IGF-I.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

P47876

applications :

Bioactivity

source :

NS0-derived Recombinant Mouse IGFBP-1 Protein, CF

USD :

432 USD

alt names :

alpha-pregnancy-associated endometrial globulin, amniotic fluid binding protein, binding protein-25, binding protein-26, binding protein-28, growth hormone independent-binding protein, hIGFBP-1, IBP1, IBP-1, IGF-binding protein 1, IGFBP1, IGFBP-1, IGF-BP25, insulin-like growth factor binding protein 1, insulin-like growth factor-binding protein 1, Placental protein 12, PP12AFBP

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after opening.

more info or order :

R&D Systems product webpage