Recombinant Equine IFN-gamma Protein | R&D Systems 1586-HG-025 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Equine IFN-gamma Protein

catalog :

1586-HG-025

quantity :

25 ug

price :

373 USD

more info or order :

R&D Systems product webpage

citations: 8

Reference
Moyo N, Westcott D, Simmonds R, Steinbach F. Equine Arteritis Virus in Monocytic Cells Suppresses Differentiation and Function of Dendritic Cells. Viruses. 2023;15: pubmed publisher
Lange Consiglio A, Romele P, Magatti M, Silini A, Idda A, Martino N, et al. Priming with inflammatory cytokines is not a prerequisite to increase immune-suppressive effects and responsiveness of equine amniotic mesenchymal stromal cells. Stem Cell Res Ther. 2020;11:99 pubmed publisher
Barrachina L, Cequier A, Romero A, Vitoria A, Zaragoza P, Vázquez F, et al. Allo-antibody production after intraarticular administration of mesenchymal stem cells (MSCs) in an equine osteoarthritis model: effect of repeated administration, MSC inflammatory stimulation, and equine leukocyte antigen (ELA) compatibility. Stem Cell Res Ther. 2020;11:52 pubmed publisher
Cassano J, Schnabel L, Goodale M, Fortier L. Inflammatory licensed equine MSCs are chondroprotective and exhibit enhanced immunomodulation in an inflammatory environment. Stem Cell Res Ther. 2018;9:82 pubmed publisher
Berghaus L, Giguere S, Bordin A, Cohen N. Effects of priming with cytokines on intracellular survival and replication of Rhodococcus equi in equine macrophages. Cytokine. 2018;102:7-11 pubmed publisher
Ziegler A, Everett H, Hamza E, Garbani M, Gerber V, Marti E, et al. Equine dendritic cells generated with horse serum have enhanced functionality in comparison to dendritic cells generated with fetal bovine serum. BMC Vet Res. 2016;12:254 pubmed
Maumus M, Roussignol G, Toupet K, Penarier G, Bentz I, Teixeira S, et al. Utility of a Mouse Model of Osteoarthritis to Demonstrate Cartilage Protection by IFNγ-Primed Equine Mesenchymal Stem Cells. Front Immunol. 2016;7:392 pubmed
Kwon S, Gewirtz A, Hurley D, Robertson T, Moore J, Vandenplas M. Disparities in TLR5 expression and responsiveness to flagellin in equine neutrophils and mononuclear phagocytes. J Immunol. 2011;186:6263-70 pubmed publisher

product information

brand :

R&D Systems

master code :

1586-HG

SKU :

1586-HG-025

product name :

Recombinant Equine IFN-gamma Protein

unit size :

25 ug

seo description :

The Recombinant Equine IFN-gamma Protein from R&D Systems is derived from E. coli. The Recombinant Equine IFN-gamma Protein has been validated for the following applications: Bioactivity.

target :

IFN-gamma

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in Sodium Succinate, Mannitol and Tween« 80 with BSA as a carrier protein.

conjugate :

Unconjugated

dilution :

Bioactivity

purity :

>97%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Equine

theoretical molecular weight :

16.7 kDa

details of functionality :

Measured in an anti-viral assay using L-929 mouse fibroblast cells infected with encephalomyocarditis (EMC) virus. Vogel, S.N. et al . (1982) Infect. Immunol. 38 :681. The ED50 for this effect is 2-8 ng/mL.

endotoxin note :

<0.01 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

BAA05876

applications :

Bioactivity

source :

E. coli-derived Recombinant Equine IFN-gamma Protein

USD :

373 USD

alt names :

IFG, IFI, IFNG, IFNgamma, IFN-gamma, Immune interferon, interferon gamma, interferon, gamma

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage