Recombinant Mouse LOX-1/OLR1 Protein, CF | R&D Systems 1564-LX-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse LOX-1/OLR1 Protein, CF

catalog :

1564-LX-050

quantity :

50 ug

price :

491 USD

more info or order :

R&D Systems product webpage

citations: 3

Reference
Roper B, Tiede C, Abdul Zani I, Cuthbert G, Jade D, Al Aufi A, et al. "Affimer" synthetic protein scaffolds block oxidized LDL binding to the LOX-1 scavenger receptor and inhibit ERK1/2 activation. J Biol Chem. 2023;299:105325 pubmed publisher
BiedroÅ„ R, KonopiÅ„ski M, Marcinkiewicz J, JÃ³zefowski S. Oxidation by neutrophils-derived HOCl increases immunogenicity of proteins by converting them into ligands of several endocytic receptors involved in antigen uptake by dendritic cells and macrophages. PLoS ONE. 2015;10:e0123293 pubmed publisher
Serke H, Nowicki M, Kosacka J, Schroder T, Kloting N, Bluher M, et al. Leptin-deficient (ob/ob) mouse ovaries show fatty degeneration, enhanced apoptosis and decreased expression of steroidogenic acute regulatory enzyme. Int J Obes (Lond). 2012;36:1047-53 pubmed publisher

product information

master code :

1564-LX

SKU :

1564-LX-050

product name :

Recombinant Mouse LOX-1/OLR1 Protein, CF

unit size :

50 ug

description :

The Recombinant Mouse LOX-1/OLR1 Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse LOX-1/OLR1 Protein, CF has been validated for the following applications: Binding Activity.

target :

LOX-1/OLR1

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Mouse

observed molecular weight :

50-60 kDa, reducing conditions

theoretical molecular weight :

36.3 kDa

gene symbol :

Olr1

details of functionality :

Measured by its binding ability in a functional ELISA. Immobilized rmLOX-1 at 5 ╡g/mL (100 ╡L/well) can bind biotinylated advanced glycation end products of bovine serum albumin (AGE-BSA) with a linear range of 0.02-1 ╡g/mL.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

AAG44998

applications :

Binding Activity

source long :

Mouse myeloma cell line, NS0-derived mouse LOX-1/OLR1 protein Arg60-Ile363, with an N-terminal 10-His tag

source short :

NS0

USD :

491 USD

alt names :

CLEC8A, CLEC8ASLOX1, C-type lectin domain family 8 member A, hLOX-1, Lectin-like oxidized LDL receptor 1, Lectin-like oxLDL receptor 1, Lectin-type oxidized LDL receptor 1, LOX1, LOX-1, LOX1ox LDL receptor 1, LOXIN, OLR1, oxidised low density lipoprotein (lectin-like) receptor 1, oxidized low density lipoprotein (lectin-like) receptor 1, oxidized low-density lipoprotein receptor 1, oxidized low-density lipoprotein receptor 1, soluble form, Ox-LDL receptor 1, SCARE1, scavenger receptor class E, member 1, SR-E1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage