Recombinant Mouse Fetuin A/AHSG Protein, CF | R&D Systems 1563-PI-050 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse Fetuin A/AHSG Protein, CF

catalog :

1563-PI-050

quantity :

50 ug

price :

432 USD

citations: 4

Reference
Zhao P, Wei Y, Sun G, Xu L, Wang T, Tian Y, et al. Fetuin-A alleviates neuroinflammation against traumatic brain injury-induced microglial necroptosis by regulating Nrf-2/HO-1 pathway. J Neuroinflammation. 2022;19:269 pubmed publisher
Chatterjee P, Seal S, Mukherjee S, Kundu R, Mukherjee S, Ray S, et al. Adipocyte fetuin-A contributes to macrophage migration into adipose tissue and polarization of macrophages. J Biol Chem. 2013;288:28324-30 pubmed publisher
Pal D, Dasgupta S, Kundu R, Maitra S, Das G, Mukhopadhyay S, et al. Fetuin-A acts as an endogenous ligand of TLR4 to promote lipid-induced insulin resistance. Nat Med. 2012;18:1279-85 pubmed publisher
Dasgupta S, Bhattacharya S, Biswas A, Majumdar S, Mukhopadhyay S, Ray S, et al. NF-kappaB mediates lipid-induced fetuin-A expression in hepatocytes that impairs adipocyte function effecting insulin resistance. Biochem J. 2010;429:451-62 pubmed publisher

product information

master code :

1563-PI

SKU :

1563-PI-050

product name :

Recombinant Mouse Fetuin A/AHSG Protein, CF

unit size :

50 ug

description :

The Recombinant Mouse Fetuin A/AHSG Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse Fetuin A/AHSG Protein, CF has been validated for the following applications: Inhibition Activity.

target :

Fetuin A/AHSG

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in Tris and NaCl.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Mouse

observed molecular weight :

58 kDa, reducing conditions

theoretical molecular weight :

37 kDa

gene symbol :

Ahsg

details of functionality :

Measured by its ability to inhibit trypsin cleavage of a fluorogenic peptide substrate, Mca-RPKPVE-Nval-WRK(Dnp)-NH2 (Catalog # ES002 ). The IC50 value is 0.20 ╡M, as measured under the described conditions.

endotoxin note :

<1.0 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

NP_038493

applications :

Inhibition Activity

source long :

Mouse myeloma cell line, NS0-derived mouse Fetuin A/AHSG protein Ala19-Ile345, with a C-terminal 10-His tag

source short :

NS0

USD :

432 USD

alt names :

A2HS, AHS, AHSG, alpha-2-HS-glycoprotein, alpha-2-Z-globulin, Ba-alpha-2-glycoprotein, FETUAba-alpha-2-glycoprotein, fetuin-A, HSGA

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 ░C as supplied. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.