Recombinant Canine GM-CSF Protein, CF | R&D Systems 1546-GM-025/CF product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Canine GM-CSF Protein, CF

catalog :

1546-GM-025/CF

quantity :

25 ug

price :

432 USD

more info or order :

R&D Systems product webpage

citations: 10

Reference
Stranahan L, Chaki S, Garcia Gonzalez D, Khalaf O, Arenas Gamboa A. Evaluation of the Efficacy of the Brucella canis RM6/66 ΔvjbR Vaccine Candidate for Protection against B. canis Infection in Mice. mSphere. 2020;5: pubmed publisher
Konduri V, Halpert M, Baig Y, Coronado R, Rodgers J, Levitt J, et al. Dendritic cell vaccination plus low-dose doxorubicin for the treatment of spontaneous canine hemangiosarcoma. Cancer Gene Ther. 2019;: pubmed publisher
Hernández Granados A, Franco Molina M, Coronado Cerda E, Zapata Benavides P, Gamboa E, Ramos Zayas Y, et al. Immunogenic potential of three transmissible venereal tumor cell lysates to prime canine-dendritic cells for cancer immunotherapy. Res Vet Sci. 2018;121:23-30 pubmed publisher
Heinrich F, Lehmbecker A, Raddatz B, Kegler K, Tipold A, Stein V, et al. Morphologic, phenotypic, and transcriptomic characterization of classically and alternatively activated canine blood-derived macrophages in vitro. PLoS ONE. 2017;12:e0183572 pubmed publisher
Guldner D, Hwang J, Cardieri M, Eren M, Ziaei P, Norton M, et al. In Vitro Evaluation of the Biological Responses of Canine Macrophages Challenged with PLGA Nanoparticles Containing Monophosphoryl Lipid A. PLoS ONE. 2016;11:e0165477 pubmed publisher
Bauer T, Olson E, Huo Y, Tuschong L, Allen J, Li Y, et al. Treatment of canine leukocyte adhesion deficiency by foamy virus vectors expressing CD18 from a PGK promoter. Gene Ther. 2011;18:553-9 pubmed publisher
Xiong W, Candolfi M, Liu C, Muhammad A, Yagiz K, Puntel M, et al. Human Flt3L generates dendritic cells from canine peripheral blood precursors: implications for a dog glioma clinical trial. PLoS ONE. 2010;5:e11074 pubmed publisher
Lange S, Altmann S, Brandt B, Adam C, Riebau F, Vogel H, et al. Investigation of immunological approaches to enhance engraftment in a 1 Gy TBI canine hematopoietic stem cell transplantation model. Exp Hematol. 2009;37:143-50 pubmed publisher
Choi E, Koo H, Shin I, Chae Y, Lee J, Han S, et al. Preventive and therapeutic effects of gene therapy using silica nanoparticles-binding of GM-CSF gene on white blood cell production in dogs with leukopenia. Exp Hematol. 2008;36:1091-7 pubmed publisher
Choi E, Shin I, Chae Y, Koo H, Lee J, Chung T, et al. Effects of GM-CSF gene transfer using silica-nanoparticles as a vehicle on white blood cell production in dogs. Exp Hematol. 2008;36:807-15 pubmed publisher

product information

master code :

1546-GM/CF

SKU :

1546-GM-025/CF

product name :

Recombinant Canine GM-CSF Protein, CF

unit size :

25 ug

description :

The Recombinant Canine GM-CSF Protein, CF from R&D Systems is derived from E. coli. The Recombinant Canine GM-CSF Protein, CF has been validated for the following applications: Bioactivity.

target :

GM-CSF

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>97%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Canine

theoretical molecular weight :

14.2 kDa

gene symbol :

CSF2

details of functionality :

Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. Kitamura, T. et al . (1989) J. Cell Physiol. 140 :323. The ED50 for this effect is 1-4 ng/mL.

endotoxin note :

<0.01 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

P48749.1

applications :

Bioactivity

source long :

E. coli -derived canine GM-CSF protein Ala18-Lys144

source short :

E. coli

USD :

432 USD

alt names :

colony stimulating factor 2 (granulocyte-macrophage), Colony-stimulating factor, CSF, CSF2, CSF-2, GMCSF, GM-CSF, GMCSFgranulocyte-macrophage colony-stimulating factor, granulocyte-macrophage colony stimulating factor, MGC131935, MGC138897, Molgramostim, molgramostin, sargramostim

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage