Recombinant Mouse Cripto Protein | R&D Systems 1538-CR-010 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse Cripto Protein

catalog :

1538-CR-010

quantity :

10 ug

price :

447 USD

more info or order :

R&D Systems product webpage

citations: 6

Reference
Balcioglu O, Heinz R, Freeman D, Gates B, Hagos B, Booker E, et al. CRIPTO antagonist ALK4L75A-Fc inhibits breast cancer cell plasticity and adaptation to stress. Breast Cancer Res. 2020;22:125 pubmed publisher
Perino M, Yamanaka S, Riordon D, Tarasova Y, Boheler K. Ascorbic acid promotes cardiomyogenesis through SMAD1 signaling in differentiating mouse embryonic stem cells. PLoS ONE. 2017;12:e0188569 pubmed publisher
Spike B, Kelber J, Booker E, Kalathur M, Rodewald R, Lipianskaya J, et al. CRIPTO/GRP78 signaling maintains fetal and adult mammary stem cells ex vivo. Stem Cell Reports. 2014;2:427-39 pubmed publisher
Rangel M, Karasawa H, Castro N, Nagaoka T, Salomon D, Bianco C. Role of Cripto-1 during epithelial-to-mesenchymal transition in development and cancer. Am J Pathol. 2012;180:2188-200 pubmed publisher
Strizzi L, Mancino M, Bianco C, Raafat A, Gonzales M, Booth B, et al. Netrin-1 can affect morphogenesis and differentiation of the mouse mammary gland. J Cell Physiol. 2008;216:824-34 pubmed publisher
Lindsley R, Gill J, Kyba M, Murphy T, Murphy K. Canonical Wnt signaling is required for development of embryonic stem cell-derived mesoderm. Development. 2006;133:3787-96 pubmed

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

1538-CR

SKU :

1538-CR-010

product name :

Recombinant Mouse Cripto Protein

Description :

The Recombinant Mouse Cripto Protein from R&D Systems is derived from NS0. The Recombinant Mouse Cripto Protein has been validated for the following applications: Binding Activity.

target :

Cripto

category :

Proteins and Enzymes

unit size :

10 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Mouse

observed molecular weight :

20-25 kDa, reducing conditions

theoretical molecular weight :

15 kDa

gene symbol :

Tdgf1

details of functionality :

Measured by its binding ability in a functional ELISA. Immobilized rmActivin RIB/Fc Chimera at 1 µg/mL (100 µL/well) can bind rmCripto with a linear range of 0.8-100 ng/mL. This protein will also bind rmNodal in a functional ELISA.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

P51865

applications :

Binding Activity

source :

NS0-derived Recombinant Mouse Cripto Protein

USD :

447 USD

alt names :

CFC-2, CR, Cripto-1, Cripto-1 growth factor, CRIPTOCRGF, Epidermal growth factor-like cripto protein CR1, TDGF1, TDGF-1, teratocarcinoma-derived growth factor 1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage