product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse TLR2 Fc Chimera Protein, CF
catalog :
1530-TR-050
quantity :
50 ug
price :
447 USD
more info or order :
R&D Systems product webpage
citations: 6
Reference
Xie X, Lv H, Liu C, Su X, Yu Z, Song S, et al. HBeAg mediates inflammatory functions of macrophages by TLR2 contributing to hepatic fibrosis. BMC Med. 2021;19:247 pubmed publisher
Maehara N, Taniguchi K, Okuno A, Ando H, Hirota A, Li Z, et al. AIM/CD5L attenuates DAMPs in the injured brain and thereby ameliorates ischemic stroke. Cell Rep. 2021;36:109693 pubmed publisher
George J, Kim S, Choi J, Patil A, Hossain F, Uyangaa E, et al. TLR2/MyD88 pathway-dependent regulation of dendritic cells by dengue virus promotes antibody-dependent enhancement via Th2-biased immunity. Oncotarget. 2017;8:106050-106070 pubmed publisher
Koymans K, Feitsma L, Brondijk T, Aerts P, Lukkien E, Lössl P, et al. Structural basis for inhibition of TLR2 by staphylococcal superantigen-like protein 3 (SSL3). Proc Natl Acad Sci U S A. 2015;112:11018-23 pubmed publisher
Raby A, Le Bouder E, Colmont C, Davies J, Richards P, Coles B, et al. Soluble TLR2 reduces inflammation without compromising bacterial clearance by disrupting TLR2 triggering. J Immunol. 2009;183:506-17 pubmed publisher
Onishi S, Honma K, Liang S, Stathopoulou P, Kinane D, Hajishengallis G, et al. Toll-like receptor 2-mediated interleukin-8 expression in gingival epithelial cells by the Tannerella forsythia leucine-rich repeat protein BspA. Infect Immun. 2008;76:198-205 pubmed
product information
brand :
R&D Systems, a Bio-Techne Brand
catalog number base :
1530-TR
SKU :
1530-TR-050
product name :
Recombinant Mouse TLR2 Fc Chimera Protein, CF
Description :
The Recombinant Mouse TLR2 Fc Chimera Protein, CF from R&D Systems is derived from Sf 21 (baculovirus). The Recombinant Mouse TLR2 Fc Chimera Protein, CF has been validated for the following applications: Binding Activity.
target :
TLR2
category :
Proteins and Enzymes
unit size :
50 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS, NaCl and PEG 3350.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
species :
Mouse
observed molecular weight :
92 kDa, reducing conditions
theoretical molecular weight :
90.4 kDa (monomer)
gene symbol :
Tlr2
details of functionality :
Measured by its binding ability in a functional ELISA. Immobilized peptidoglycan at 10 µg/mL (100 µL/well) can bind recombinant mouse TLR2 Fc Chimera with a linear range of 0.04-30 µg/mL.
endotoxin note :
<0.10 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
Q9QUN7
applications :
Binding Activity
source :
Sf 21 (baculovirus)-derived Recombinant Mouse TLR2 Fc Chimera Protein
USD :
447 USD
alt names :
CD282, CD282 antigen, TIL4CD282, toll/interleukin 1 receptor-like 4, Toll/interleukin-1 receptor-like protein 4, toll-like receptor 2
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.