Recombinant Mouse TIM-3 Fc Chimera Protein, CF | R&D Systems 1529-TM-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse TIM-3 Fc Chimera Protein, CF

catalog :

1529-TM-050

quantity :

50 ug

price :

423 USD

more info or order :

R&D Systems product webpage

citations: 2

Reference
Matsumura T, Sugawara Y, Yutani M, Amatsu S, Yagita H, Kohda T, et al. Botulinum toxin A complex exploits intestinal M cells to enter the host and exert neurotoxicity. Nat Commun. 2015;6:6255 pubmed publisher
Leitner J, Rieger A, Pickl W, Zlabinger G, Grabmeier Pfistershammer K, Steinberger P. TIM-3 does not act as a receptor for galectin-9. PLoS Pathog. 2013;9:e1003253 pubmed publisher

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

1529-TM

SKU :

1529-TM-050

product name :

Recombinant Mouse TIM-3 Fc Chimera Protein, CF

Description :

The Recombinant Mouse TIM-3 Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse TIM-3 Fc Chimera Protein, CF has been validated for the following applications: Binding Activity.

target :

TIM-3

category :

Proteins and Enzymes

unit size :

50 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Mouse

observed molecular weight :

67-80 kDa, reducing conditions

theoretical molecular weight :

45.6 kDa (monomer)

gene symbol :

Havcr2

details of functionality :

Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human Galectin-9 (Catalog # 2045-GA ) at 500 ng/mL can bind recombinant mouse TIM-3 Fc Chimera with an apparent KD 10 nM.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

AAL65156

applications :

Binding Activity

source :

NS0-derived Recombinant Mouse TIM-3 Fc Chimera Protein

USD :

423 USD

alt names :

CD366, FLJ14428, HAVcr-2, HAVCR2, hepatitis A virus cellular receptor 2, kidney injury molecule-3, KIM-3, SPTCL, T cell immunoglobulin mucin 3, T cell immunoglobulin mucin-3, T-cell immunoglobulin and mucin domain-containing protein 3, TIM 3, Tim-3, TIM3, TIM3 T-cell membrane protein 3, TIMD3, TIMD-3, TIMD3KIM-3

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage