Recombinant Mouse Cathepsin L Protein, CF | R&D Systems 1515-CY-010 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse Cathepsin L Protein, CF

catalog :

1515-CY-010

quantity :

10 ug

price :

423 USD

more info or order :

R&D Systems product webpage

citations: 8

Reference
Ilgová J, Kavanová L, Matiašková K, Salat J, Kasný M. Effect of cysteine peptidase inhibitor of Eudiplozoon nipponicum (Monogenea) on cytokine expression of macrophages in vitro. Mol Biochem Parasitol. 2020;235:111248 pubmed publisher
Ilgová J, Jedličková L, Dvorakova H, Benovics M, Mikes L, Janda L, et al. A novel type I cystatin of parasite origin with atypical legumain-binding domain. Sci Rep. 2017;7:17526 pubmed publisher
Tohda C, Tohda M. Extracellular cathepsin L stimulates axonal growth in neurons. BMC Res Notes. 2017;10:613 pubmed publisher
Zhou X, Paushter D, Feng T, Sun L, Reinheckel T, Hu F. Lysosomal processing of progranulin. Mol Neurodegener. 2017;12:62 pubmed publisher
Parks A, McFaline Figueroa J, Coogan A, Poe Yamagata E, Guldberg R, Platt M, et al. Supraspinatus tendon overuse results in degenerative changes to tendon insertion region and adjacent humeral cartilage in a rat model. J Orthop Res. 2017;35:1910-1918 pubmed publisher
McComb S, Shutinoski B, Thurston S, Cessford E, Kumar K, Sad S. Cathepsins limit macrophage necroptosis through cleavage of Rip1 kinase. J Immunol. 2014;192:5671-8 pubmed publisher
Zeeuwen P, van Vlijmen Willems I, Cheng T, Rodijk Olthuis D, Hitomi K, Hara Nishimura I, et al. The cystatin M/E-cathepsin L balance is essential for tissue homeostasis in epidermis, hair follicles, and cornea. FASEB J. 2010;24:3744-55 pubmed publisher
Duncan E, Muratore Schroeder T, Cook R, Garcia B, Shabanowitz J, Hunt D, et al. Cathepsin L proteolytically processes histone H3 during mouse embryonic stem cell differentiation. Cell. 2008;135:284-94 pubmed publisher

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

1515-CY

SKU :

1515-CY-010

product name :

Recombinant Mouse Cathepsin L Protein, CF

Description :

The Recombinant Mouse Cathepsin L Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse Cathepsin L Protein, CF has been validated for the following applications: Enzyme Activity.

target :

Cathepsin L

category :

Proteins and Enzymes

unit size :

10 ug

buffer :

Supplied as a 0.2 µm filtered solution in Tris and NaCl.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Mouse

observed molecular weight :

35-40 kDa, reducing conditions

theoretical molecular weight :

37 kDa

gene symbol :

Ctsl

details of functionality :

Measured by its ability to cleave the fluorogenic peptide substrate Z-LR-AMC (Catalog # ES008 ). The specific activity is 5,000 pmol/min/µg, as measured under the described conditions.

endotoxin note :

<1.0 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

P06797

applications :

Enzyme Activity

source :

NS0-derived Recombinant Mouse Cathepsin L Protein

USD :

423 USD

alt names :

cathepsin L, cathepsin L1, CATL, CTSL, CTSL1, CTSLEC 3.4.22.15, EC 3.4.22, FLJ31037, Major excreted protein, MEP

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 °C as supplied. 3 months, -20 to -70 °C under sterile conditions after opening.

more info or order :

R&D Systems product webpage