Recombinant Canine TNF-alpha Protein, CF | R&D Systems 1507-CT-025/CF product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Canine TNF-alpha Protein, CF

catalog :

1507-CT-025/CF

quantity :

25 ug

price :

423 USD

more info or order :

R&D Systems product webpage

citations: 7

Reference
Thalmensi J, Pliquet E, Liard C, Chamel G, Kreuz C, Bestetti T, et al. A DNA telomerase vaccine for canine cancer immunotherapy. Oncotarget. 2019;10:3361-3372 pubmed publisher
Konduri V, Halpert M, Baig Y, Coronado R, Rodgers J, Levitt J, et al. Dendritic cell vaccination plus low-dose doxorubicin for the treatment of spontaneous canine hemangiosarcoma. Cancer Gene Ther. 2019;: pubmed publisher
Lahey K, Ronaghan N, Shang J, Dion S, Desilets A, Leduc R, et al. Signaling pathways induced by serine proteases to increase intestinal epithelial barrier function. PLoS ONE. 2017;12:e0180259 pubmed publisher
Roatt B, Aguiar Soares R, Reis L, Cardoso J, Mathias F, de Brito R, et al. A Vaccine Therapy for Canine Visceral Leishmaniasis Promoted Significant Improvement of Clinical and Immune Status with Reduction in Parasite Burden. Front Immunol. 2017;8:217 pubmed publisher
Russell K, Chow N, Dukoff D, Gibson T, LaMarre J, Betts D, et al. Characterization and Immunomodulatory Effects of Canine Adipose Tissue- and Bone Marrow-Derived Mesenchymal Stromal Cells. PLoS ONE. 2016;11:e0167442 pubmed publisher
Genini S, Beltran W, Aguirre G. Up-regulation of tumor necrosis factor superfamily genes in early phases of photoreceptor degeneration. PLoS ONE. 2013;8:e85408 pubmed publisher
Willenbrock S, Braun O, Baumgart J, Lange S, Junghanss C, Heisterkamp A, et al. TNF-? induced secretion of HMGB1 from non-immune canine mammary epithelial cells (MTH53A). Cytokine. 2012;57:210-20 pubmed publisher

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

1507-CT/CF

SKU :

1507-CT-025/CF

product name :

Recombinant Canine TNF-alpha Protein, CF

Description :

The Recombinant Canine TNF-alpha Protein, CF from R&D Systems is derived from E. coli. The Recombinant Canine TNF-alpha Protein, CF has been validated for the following applications: Bioactivity.

target :

TNF-alpha

category :

Proteins and Enzymes

unit size :

25 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS.

conjugate :

Unconjugated

purity :

>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Canine

theoretical molecular weight :

17.3 kDa

gene symbol :

TNF

details of functionality :

Measured in a cytotoxicity assay using L-929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D. Matthews, N. and M.L. Neale (1987) in Lymphokines and Interferons, A Practical Approach. Clemens, M.J. et al . (eds): IRL Press. 221. The ED50 for this effect is 80-500 pg/mL.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

CAA64403

applications :

Bioactivity

source :

E. coli-derived Recombinant Canine TNF-alpha Protein

USD :

423 USD

alt names :

APC1 protein, Cachectin, Cachetin, DIF, TNF, TNF, monocyte-derived, TNF-a, TNFA, TNFalpha, TNF-alphacachectin, TNFATNF, macrophage-derived, TNFG1F, TNFSF1A, TNFSF2, TNFSF2TNF superfamily, member 2, tumor necrosis factor, tumor necrosis factor (TNF superfamily, member 2), tumor necrosis factor alpha, Tumor necrosis factor ligand superfamily member 2, tumor necrosis factor-alpha

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage