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company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse TrkB Protein, CF
catalog :
1494-TB-025/CF
quantity :
25 ug
price :
423 USD
more info or order :
R&D Systems product webpage
citations: 2
Reference
Matsumura Y, Yamashita T, Sasaki A, Nakata E, Kohno K, Masuda T, et al. A novel P2X4 receptor-selective antagonist produces anti-allodynic effect in a mouse model of herpetic pain. Sci Rep. 2016;6:32461 pubmed publisher
Snapyan M, Lemasson M, Brill M, Blais M, Massouh M, Ninkovic J, et al. Vasculature guides migrating neuronal precursors in the adult mammalian forebrain via brain-derived neurotrophic factor signaling. J Neurosci. 2009;29:4172-88 pubmed publisher
product information
brand :
R&D Systems, a Bio-Techne Brand
catalog number base :
1494-TB/CF
SKU :
1494-TB-025/CF
product name :
Recombinant Mouse TrkB Protein, CF
Description :
The Recombinant Mouse TrkB Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse TrkB Protein, CF has been validated for the following applications: Bioactivity.
target :
TrkB
category :
Proteins and Enzymes
unit size :
25 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
species :
Mouse
observed molecular weight :
75-100 kDa, reducing conditions
theoretical molecular weight :
45.9 kDa
gene symbol :
Ntrk2
details of functionality :
Measured by its ability to inhibit BDNF-induced proliferation of BaF-TrkB-BD mouse pro-B cells transfected with TrkB. The ED50 for this effect is 0.5-3.5 µg/mL in the presence recombinant human BDNF and 5 µg/mL of a cross-linking antibody, Mouse Anti-polyHistidine Monoclonal Antibody (Catalog # MAB050 ).
endotoxin note :
<0.10 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
P15209
applications :
Bioactivity
source :
NS0-derived Recombinant Mouse TrkB Protein
extended description :
His-tag
USD :
423 USD
product details :
His-tag
alt names :
BDNF/NT-3 growth factors receptor, EC 2.7.10, EC 2.7.10.1, GP145-TrkB, Neurotrophic tyrosine kinase receptor type 2, neurotrophic tyrosine kinase, receptor, type 2, NTRK2, trk-B, TrkB tyrosine kinase, TRKBBDNF-tropomyosine receptor kinase B, tyrosine kinase receptor B
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.