Recombinant Human IL-27 Ra/WSX-1/TCCR Fc Chimera Protein, CF | R&D Systems 1479-TC-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human IL-27 Ra/WSX-1/TCCR Fc Chimera Protein, CF

catalog :

1479-TC-050

quantity :

50 ug

price :

423 USD

more info or order :

R&D Systems product webpage

citations: 2

Reference
Liu S, Han J, Gong H, Li Y, Bao X, Qi J, et al. Soluble interleukin-27 receptor alpha is a valuable prognostic biomarker for acute graft-versus-host disease after allogeneic haematopoietic stem cell transplantation. Sci Rep. 2018;8:10328 pubmed publisher
Dietrich C, Candon S, Ruemmele F, Devergne O. A soluble form of IL-27R? is a natural IL-27 antagonist. J Immunol. 2014;192:5382-9 pubmed publisher

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

1479-TC

SKU :

1479-TC-050

product name :

Recombinant Human IL-27 Ra/WSX-1/TCCR Fc Chimera Protein, CF

Description :

The Recombinant Human IL-27 Ra/WSX-1/TCCR Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Human IL-27 Ra/WSX-1/TCCR Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.

target :

IL-27 R alpha/WSX-1/TCCR

category :

Proteins and Enzymes

unit size :

50 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.

species :

Human

observed molecular weight :

100-110 kDa, reducing conditions

theoretical molecular weight :

79 kDa (monomer)

gene symbol :

IL27RA

details of functionality :

Measured by its ability to inhibit IL-27 anti-viral activity using HepG2 human hepatocellular carcinoma cells infected with encephalomyocarditis (EMC) virus. Bender H. et al . (2009) Hepatology 50 :585. The ED50 for this effect is 0.75-4.5 µg/mL.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

Q6UWB1

applications :

Bioactivity

source :

NS0-derived Recombinant Human IL-27 Ra/WSX-1/TCCR Fc Chimera Protein

USD :

423 USD

alt names :

class I cytokine receptor, CRL1IL-27R, Cytokine receptor-like 1, IL-27 R alpha, IL27R, IL27R alpha, IL27RA, IL-27RA, IL-27R-alpha, interleukin 27 receptor, alpha, interleukin-27 receptor subunit alpha, TCCR, TCCRIL-27 receptor subunit alpha, T-cell cytokine receptor type 1, Type I T-cell cytokine receptor, WSX-1, WSX1IL-27R subunit alpha, zcytor1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage