product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human Coagulation Factor II/Thrombin Protein, CF
catalog :
1473-SE-010
quantity :
10 ug
price :
434 USD
more info or order :
citations: 3
Reference
Herum K, Romaine A, Wang A, Melleby A, Strand M, Pacheco J, et al. Syndecan-4 Protects the Heart From the Profibrotic Effects of Thrombin-Cleaved Osteopontin. J Am Heart Assoc. 2020;9:e013518 pubmed publisher
Mogami H, Keller P, Shi H, Word R. Effect of thrombin on human amnion mesenchymal cells, mouse fetal membranes, and preterm birth. J Biol Chem. 2014;289:13295-307 pubmed publisher
Wu F, Wang Q, Zhang Z, Huang S, Yuan W, Liu J, et al. Identifying serological biomarkers of hepatocellular carcinoma using surface-enhanced laser desorption/ionization-time-of-flight mass spectroscopy. Cancer Lett. 2009;279:163-70 pubmed publisher
product information
brand :
R&D Systems, a Bio-Techne Brand
catalog number base :
1473-SE
SKU :
1473-SE-010
product name :
Recombinant Human Coagulation Factor II/Thrombin Protein, CF
Description :
The Recombinant Human Coagulation Factor II/Thrombin Protein, CF from R&D Systems is derived from NS0. The Recombinant Human Coagulation Factor II/Thrombin Protein, CF has been validated for the following applications: Enzyme Activity.
target :
Coagulation Factor II/Thrombin
category :
Proteins and Enzymes
unit size :
10 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in HEPES and NaCl.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Human
observed molecular weight :
12 kDa, 21 kDa and 23 kDa, reducing conditions
theoretical molecular weight :
4 kDa (light chain A), 31 kDa (heavy chain B), 14 kDa (C-terminal fragment)
gene symbol :
F2
details of functionality :
Measured by its ability to cleave the fluorogenic peptide substrate Boc-VPR-AMC (Catalog # ES011 ). The specific activity is 20,000 pmol/min/µg, as measured under the described conditions.
endotoxin note :
<1.0 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
P00734
applications :
Enzyme Activity
source :
NS0-derived Recombinant Human Coagulation Factor II/Thrombin Protein
USD :
434 USD
alt names :
Coagulation Factor II, coagulation factor II (thrombin) receptor-like 2, Coagulation factor II receptor-like 2, Coagulation factor II receptor-like 2 (protease-actovated receptor 3), F2, PAR-3, PAR3proteinase-activated receptor 3, protease-activated receptor 3, proteinase-activated receptor-3, PT, serine protease, Thrombin, Thrombin receptor-like 2
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 °C as supplied. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.