Recombinant Human Serpin F2/alpha 2-Antiplasmin Protein, CF | R&D Systems 1470-PI product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Serpin F2/alpha 2-Antiplasmin Protein, CF

catalog :

1470-PI

quantity :

10 ug

price :

339 USD

citations: 4

Reference
Wang J, Zhang Y, Sze S, Van de Weg S, Vernooij F, Schoneveld A, et al. Lowering Low-Density Lipoprotein Particles in Plasma Using Dextran Sulphate Co-Precipitates Procoagulant Extracellular Vesicles. Int J Mol Sci. 2017;19: pubmed publisher
Zhang Y, Vernooij F, Ibrahim I, Ooi S, Gijsberts C, Schoneveld A, et al. Extracellular Vesicle Proteins Associated with Systemic Vascular Events Correlate with Heart Failure: An Observational Study in a Dyspnoea Cohort. PLoS ONE. 2016;11:e0148073 pubmed publisher
Memari N, Jiang W, Diamandis E, Luo L. Enzymatic properties of human kallikrein-related peptidase 12 (KLK12). Biol Chem. 2007;388:427-35 pubmed
Cortesio C, Jiang W. Mannan-binding lectin-associated serine protease 3 cleaves synthetic peptides and insulin-like growth factor-binding protein 5. Arch Biochem Biophys. 2006;449:164-70 pubmed

product information

brand :

R&D Systems

master code :

1470-PI

SKU :

1470-PI-010

product name :

Recombinant Human Serpin F2/alpha 2-Antiplasmin Protein, CF

description :

The Recombinant Human Serpin F2/alpha 2-Antiplasmin Protein, CF from R&D Systems is derived from NS0. The Recombinant Human Serpin F2/alpha 2-Antiplasmin Protein, CF has been validated for the following applications: Inhibition Activity.

target :

Serpin F2/alpha 2-Antiplasmin

category :

Proteins and Enzymes

unit size :

10 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in Tris and NaCl.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

observed molecular weight :

67 kDa, reducing conditions

theoretical molecular weight :

53 kDa

gene symbol :

SERPINF2

details of functionality :

Measured by its ability to inhibit trypsin cleavage of a fluorogenic peptide substrate, Mca-RPKPVE-Nval-WRK(Dnp)-NH2 (Catalog # ES002 ). The IC50 value is 2.0 nM, as measured under the described conditions.

endotoxin note :

<1.0 EU per 1 µg of the protein by the LAL method.

catalog number base :

1470-PI

accessionNumbers :

P08697

applications :

Inhibition Activity

source :

Mouse myeloma cell line, NS0-derived human Serpin F2/alpha 2-Antiplasmin protein Met28-Lys491, with a C-terminal 10-His tag

2020 USD :

339

2021 USD :

339 USD

alt names :

AAPclade F (alpha-2 antiplasmin, alpha 2-Antiplasmin, Alpha-2-AP, Alpha-2-PI, Alpha-2-plasmin inhibitor, pigment epithelium derived factor), member 2, Serpin F2, serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epitheliumderived factor), member 2

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 °C as supplied. 3 months, -20 to -70 °C under sterile conditions after reconstitution.