Recombinant Mouse Fc gamma RIIB/CD32b Protein, CF | R&D Systems 1460-CD-050 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse Fc gamma RIIB/CD32b Protein, CF

catalog :

1460-CD-050

quantity :

50 ug

price :

432 USD

citations: 5

Reference
Taghipour Mirakmahaleh R, Morin F, Zhang Y, Bourhoven L, B xe9 land L, Zhou Q, et al. Turncoat antibodies unmasked in a model of autoimmune demyelination: from biology to therapy. bioRxiv. 2024;: pubmed publisher
Iyer R, Edwards D, Kolb P, Rau xe9 H, Nelson C, Epperson M, et al. The secreted protein Cowpox Virus 14 contributes to viral virulence and immune evasion by engaging Fc-gamma-receptors. PLoS Pathog. 2022;18:e1010783 pubmed publisher
Dodagatta Marri E, Ma H, Liang B, Li J, Meyer D, Chen S, et al. Integrin αvβ8 on T cells suppresses anti-tumor immunity in multiple models and is a promising target for tumor immunotherapy. Cell Rep. 2021;36:109309 pubmed publisher
Iskenderian A, Liu N, Deng Q, Huang Y, Shen C, Palmieri K, et al. Myostatin and activin blockade by engineered follistatin results in hypertrophy and improves dystrophic pathology in mdx mouse more than myostatin blockade alone. Skelet Muscle. 2018;8:34 pubmed publisher
Shanmugarajan S, Beeson C, Reddy S. Osteoclast inhibitory peptide-1 binding to the Fc gammaRIIB inhibits osteoclast differentiation. Endocrinology. 2010;151:4389-99 pubmed publisher

product information

master code :

1460-CD

SKU :

1460-CD-050

product name :

Recombinant Mouse Fc gamma RIIB/CD32b Protein, CF

unit size :

50 ug

description :

The Recombinant Mouse Fc gamma RIIB/CD32b Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse Fc gamma RIIB/CD32b Protein, CF has been validated for the following applications: Binding Activity.

target :

Fc gamma RIIB/CD32b

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Mouse

observed molecular weight :

30-40 kDa, reducing conditions

theoretical molecular weight :

22 kDa

gene symbol :

Fcgr2b

details of functionality :

Measured by its ability to bind mouse IgG with an estimated KDá á150 nM.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

P08101

applications :

Binding Activity

source long :

Mouse myeloma cell line, NS0-derived mouse Fc gamma RIIB/CD32b protein Thr30-Arg207, with a C-terminal 10-His tag

source short :

NS0

USD :

432 USD

alt names :

CD32 antigen, CD32b, CD32Fc fragment of IgG, low affinity II, receptor for (CD32), CDw32, Fc fragment of IgG, low affinity IIb, receptor (CD32), Fc fragment of IgG, low affinity IIb, receptor for (CD32), Fc gamma RIIb, FCG2, Fc-gamma RII-b, fc-gamma-RIIb, FCGR2, FCGR2B, FcgRIIB, fcRII-b, FCRIIB, IGFR2, IgG Fc receptor II-b, low affinity immunoglobulin gamma Fc region receptor II-b

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.