Recombinant Human HTRA2/Omi Protein, CF | R&D Systems 1458-HT-100 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human HTRA2/Omi Protein, CF

catalog :

1458-HT-100

quantity :

100 ug

price :

423 USD

more info or order :

R&D Systems product webpage

citations: 5

Reference
Kaur G, Stallmann D, Schanze N, Laumann R, Heger L, Steinfurt J, et al. Extracellular HtrA2 Induces Apoptosis in Human Umbilical Vein Endothelial Cells. Int J Mol Sci. 2019;20: pubmed publisher
Singh H, Nero T, Wang Y, Parker M, Nie G. Activity-modulating monoclonal antibodies to the human serine protease HtrA3 provide novel insights into regulating HtrA proteolytic activities. PLoS ONE. 2014;9:e108235 pubmed publisher
Chauhan D, Tian Z, Zhou B, Kuhn D, Orlowski R, Raje N, et al. In vitro and in vivo selective antitumor activity of a novel orally bioavailable proteasome inhibitor MLN9708 against multiple myeloma cells. Clin Cancer Res. 2011;17:5311-21 pubmed publisher
Johnson F, Kaplitt M. Novel mitochondrial substrates of omi indicate a new regulatory role in neurodegenerative disorders. PLoS ONE. 2009;4:e7100 pubmed publisher
Huttunen H, GUENETTE S, Peach C, Greco C, Xia W, Kim D, et al. HtrA2 regulates beta-amyloid precursor protein (APP) metabolism through endoplasmic reticulum-associated degradation. J Biol Chem. 2007;282:28285-95 pubmed

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

1458-HT

SKU :

1458-HT-100

product name :

Recombinant Human HTRA2/Omi Protein, CF

Description :

The Recombinant Human HTRA2/Omi Protein, CF from R&D Systems is derived from E. coli. The Recombinant Human HTRA2/Omi Protein, CF has been validated for the following applications: Enzyme Activity.

target :

HTRA2/Omi

category :

Proteins and Enzymes

unit size :

100 ug

buffer :

Supplied as a 0.2 µm filtered solution in HEPES, NaCl, DTT and Glycerol.

conjugate :

Unconjugated

purity :

>85%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

observed molecular weight :

38 kDa, reducing conditions

theoretical molecular weight :

36 kDa

gene symbol :

HTRA2

details of functionality :

Measured by its ability to cleave beta-casein. 95% cleavage of beta-casein, as measured under the described conditions.

accessionNumbers :

O43464

applications :

Enzyme Activity

source :

E. coli-derived Recombinant Human HTRA2/Omi Protein

USD :

423 USD

alt names :

High temperature requirement protein A2, HtrA serine peptidase 2, HtrA2, HtrA-like serine protease, Omi, OMIOmi stress-regulated endoprotease, PARK13EC 3.4.21.108, PRSS25, PRSS25serine, 25, Serine protease 25, serine protease HTRA2, mitochondrial, Serine proteinase OMI

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 °C as supplied. 3 months, -20 to -70 °C under sterile conditions after opening.

more info or order :

R&D Systems product webpage