Recombinant Mouse PDGF-CC Protein | R&D Systems 1447-PC-025 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse PDGF-CC Protein

catalog :

1447-PC-025

quantity :

25 ug

price :

432 USD

citations: 7

Reference
Geng Y, Li L, Yan J, Liu K, Yang A, Zhang L, et al. PEAR1 regulates expansion of activated fibroblasts and deposition of extracellular matrix in pulmonary fibrosis. Nat Commun. 2022;13:7114 pubmed publisher
Seki T, Hosaka K, Lim S, Fischer C, Honek J, Yang Y, et al. Endothelial PDGF-CC regulates angiogenesis-dependent thermogenesis in beige fat. Nat Commun. 2016;7:12152 pubmed publisher
Hayes B, Riehle K, Shimizu Albergine M, Bauer R, Hudkins K, Johansson F, et al. Activation of platelet-derived growth factor receptor alpha contributes to liver fibrosis. PLoS ONE. 2014;9:e92925 pubmed publisher
Jackman K, Kahles T, Lane D, Garcia Bonilla L, Abe T, Capone C, et al. Progranulin deficiency promotes post-ischemic blood-brain barrier disruption. J Neurosci. 2013;33:19579-89 pubmed publisher
Yang X, Zou H, Jung G, Richard G, Linke S, Ader M, et al. Nonneuronal control of the differential distribution of myelin along retinal ganglion cell axons in the mouse. Invest Ophthalmol Vis Sci. 2013;54:7819-27 pubmed publisher
Morrison C, Mancini S, Cipollone J, Kappelhoff R, Roskelley C, Overall C. Microarray and proteomic analysis of breast cancer cell and osteoblast co-cultures: role of osteoblast matrix metalloproteinase (MMP)-13 in bone metastasis. J Biol Chem. 2011;286:34271-85 pubmed publisher
Crawford Y, Kasman I, Yu L, ZHONG C, Wu X, Modrusan Z, et al. PDGF-C mediates the angiogenic and tumorigenic properties of fibroblasts associated with tumors refractory to anti-VEGF treatment. Cancer Cell. 2009;15:21-34 pubmed publisher

product information

brand :

R&D Systems, a Bio-Techne brand

catalog number base :

1447-PC

SKU :

1447-PC-025

product name :

Recombinant Mouse PDGF-CC Protein

description :

The Recombinant Mouse PDGF-CC Protein from R&D Systems is derived from E. coli. The Recombinant Mouse PDGF-CC Protein has been validated for the following applications: Bioactivity.

target :

PDGF-CC

unit size :

25 ug

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>97%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Mouse

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

theoretical molecular weight :

13.4 kDa (monomer)

gene symbol :

Pdgfc

details of functionality :

Measured in a cell proliferation assay using NR6R-3T3 mouse fibroblast cells. Raines, E.W. et al . (1985) Methods Enzymol. 109 :749. The ED50 for this effect is 70-350 ng/mL.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

Q8CI19

applications :

Bioactivity

product keywords :

1447-PC, rmPDGF-CC, mPDGF-CC,, 1447PC, cytokinegrowthfact, PDGFCC, PDGF CC, PDGF-C

source :

E. coli-derived Recombinant Mouse PDGF-CC Protein

USD :

423

USD 2025 :

432 USD