product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Rhesus Macaque/Cynomolgus IFN-alpha Protein
catalog :
14110-1
quantity :
100000 UN
price :
493 USD
more info or order :
R&D Systems product webpage
citations: 2
Reference
Gervais A, Le Floc h C, Le Voyer T, Bizien L, Bohlen J, Celmeli F, et al. A sensitive assay for measuring whole-blood responses to type I IFNs. Proc Natl Acad Sci U S A. 2024;121:e2402983121 pubmed publisher
Dudek A, Yunis C, Harrison L, Kumar S, Hawkinson R, Cooley S, et al. First in human phase I trial of 852A, a novel systemic toll-like receptor 7 agonist, to activate innate immune responses in patients with advanced cancer. Clin Cancer Res. 2007;13:7119-25 pubmed
product information
master code :
14110-1
SKU :
14110-1
product name :
Recombinant Rhesus Macaque/Cynomolgus IFN-alpha Protein
unit size :
100000 UN
description :
The Recombinant Rhesus Macaque/Cynomolgus IFN-alpha Protein from R&D Systems is derived from E. coli. The Recombinant Rhesus Macaque/Cynomolgus IFN-alpha Protein has been validated for the following applications: Bioactivity.
target :
IFN-alpha
category :
Proteins and Enzymes
buffer :
Phosphate buffered saline (PBS) containing 0.1% bovine serum albumin (BSA)
conjugate :
Unconjugated
purity :
>98%, by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie« Blue stain.
species :
Cynomolgus Monkey
theoretical molecular weight :
19.5 kDa
details of functionality :
Interferon was titrated with the use of the cytopathic effect inhibition assay as listed. The protein has similar activity to Human IFN Alpha 2 on human, rhesus and bovine cells. . Bovine (MDBK/VSV) û performed as described [Rubinstein et al. (1981) J. Virol. 37(2):755] The EC50 for interferon in this assay is ~5 U/ml. . Human (A549/EMCV) û performed as described [Budd et al. (1985) Canc. Chem. Pharm. 12:39]. The EC50 for interferon in this assay is ~1 U/ml. .
endotoxin note :
<1.0 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
XM_001107516
applications :
Bioactivity
source long :
E. coli -derived cynomolgus monkey IFN-alpha protein
source short :
E. coli
USD :
493 USD
alt names :
IFNA, IFNA2, IFNA2b, IFNalpha, IFN-alphaA, INFA2, interferon alpha 2, LeIF D
storage :
Store the unopened product at -20 to -70 ░C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.