Recombinant Mouse B7-H3 Protein, CF | R&D Systems 1397-B3-050/CF product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse B7-H3 Protein, CF

catalog :

1397-B3-050/CF

quantity :

50 ug

price :

432 USD

citations: 8

Reference
Burvenich I, Parakh S, Lee F, Guo N, Liu Z, Gan H, et al. Molecular imaging of T cell co-regulator factor B7-H3 with 89Zr-DS-5573a. Theranostics. 2018;8:4199-4209 pubmed publisher
Wei X, Li K, Zhang G, Huang Y, Lv J, Li M, et al. B7-H3 promoted proliferation of mouse spermatogonial stem cells via the PI3K signaling pathway. Oncotarget. 2018;9:1542-1552 pubmed publisher
Chen X, Li Y, Blankson S, Liu M, Huang D, Redmond H, et al. B7-H3 Augments Inflammatory Responses and Exacerbates Brain Damage via Amplifying NF-?B p65 and MAPK p38 Activation during Experimental Pneumococcal Meningitis. PLoS ONE. 2017;12:e0171146 pubmed publisher
Gu W, Zhang X, Yan Y, Wang Y, Huang L, Wang M, et al. B7-H3 participates in the development of Asthma by augmentation of the inflammatory response independent of TLR2 pathway. Sci Rep. 2017;7:40398 pubmed publisher
Li Y, Huang J, Foley N, Xu Y, Li Y, Pan J, et al. B7H3 ameliorates LPS-induced acute lung injury via attenuation of neutrophil migration and infiltration. Sci Rep. 2016;6:31284 pubmed publisher
Lutz A, Bachawal S, Drescher C, Pysz M, Willmann J, Gambhir S. Ultrasound molecular imaging in a human CD276 expression-modulated murine ovarian cancer model. Clin Cancer Res. 2014;20:1313-22 pubmed publisher
Chen X, Quinn E, Ni H, Wang J, Blankson S, Redmond H, et al. B7-H3 participates in the development of experimental pneumococcal meningitis by augmentation of the inflammatory response via a TLR2-dependent mechanism. J Immunol. 2012;189:347-55 pubmed publisher
Zhang G, Wang J, Kelly J, Gu G, Hou J, Zhou Y, et al. B7-H3 augments the inflammatory response and is associated with human sepsis. J Immunol. 2010;185:3677-84 pubmed publisher

product information

master code :

1397-B3/CF

SKU :

1397-B3-050/CF

product name :

Recombinant Mouse B7-H3 Protein, CF

unit size :

50 ug

description :

The Recombinant Mouse B7-H3 Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse B7-H3 Protein, CF has been validated for the following applications: Bioactivity.

target :

B7-H3

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.

species :

Mouse

observed molecular weight :

38-45 kDa, reducing conditions

theoretical molecular weight :

24.8 kDa

gene symbol :

Cd276

details of functionality :

Measured by its ability to enhance anti-CD3-induced proliferation of mouse CD3+ T cells. The ED50 for this effect is typically 1.5-7.5 ╡g/mL.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

Q8VE98.1

applications :

Bioactivity

source long :

Mouse myeloma cell line, NS0-derived mouse B7-H3 protein Val29-Phe244, with a C-terminal 10-His tag

source short :

NS0

USD :

432 USD

alt names :

B7H3, B7H34Ig-B7-H3, B7-H3B7 homolog 3, CD276, CD276 antigen, CD276 molecule, Costimulatory molecule

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.