This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
R&D Systems
product type :
protein
product name :
Recombinant Human sFRP-1 (Histidine-tagged) Protein
catalog :
1384-SF
quantity :
25 ug
price :
329 USD
citations: 9
Reference
Skaria T, Bächli E, Schoedon G. WIF1 prevents Wnt5A mediated LIMK/CFL phosphorylation and adherens junction disruption in human vascular endothelial cells. J Inflamm (Lond). 2017;14:10 pubmed publisher
Skaria T, Bächli E, Schoedon G. Wnt5A/Ryk signaling critically affects barrier function in human vascular endothelial cells. Cell Adh Migr. 2017;11:24-38 pubmed publisher
Maltseva I, Chan M, Kalus I, Dierks T, Rosen S. The SULFs, extracellular sulfatases for heparan sulfate, promote the migration of corneal epithelial cells during wound repair. PLoS ONE. 2013;8:e69642 pubmed publisher
Shen X, Ying H, Yue B. Wnt activation by wild type and mutant myocilin in cultured human trabecular meshwork cells. PLoS ONE. 2012;7:e44902 pubmed publisher
Gogolla N, Galimberti I, Deguchi Y, Caroni P. Wnt signaling mediates experience-related regulation of synapse numbers and mossy fiber connectivities in the adult hippocampus. Neuron. 2009;62:510-25 pubmed publisher
Kobune M, Kawano Y, Takahashi S, Takada K, Murase K, Iyama S, et al. Interaction with human stromal cells enhances CXCR4 expression and engraftment of cord blood Lin(-)CD34(-) cells. Exp Hematol. 2008;36:1121-31 pubmed publisher
Lane N, Nevitt M, Lui L, de Leon P, Corr M. Wnt signaling antagonists are potential prognostic biomarkers for the progression of radiographic hip osteoarthritis in elderly Caucasian women. Arthritis Rheum. 2007;56:3319-25 pubmed
Wawrzak D, Metioui M, Willems E, Hendrickx M, De Genst E, Leyns L. Wnt3a binds to several sFRPs in the nanomolar range. Biochem Biophys Res Commun. 2007;357:1119-23 pubmed
Lindsley R, Gill J, Kyba M, Murphy T, Murphy K. Canonical Wnt signaling is required for development of embryonic stem cell-derived mesoderm. Development. 2006;133:3787-96 pubmed
product information
brand :
R&D Systems
master code :
1384-SF
SKU :
1384-SF-025
product name :
Recombinant Human sFRP-1 (Histidine-tagged) Protein
description :
The Recombinant Human sFRP-1 (Histidine-tagged) Protein from R&D Systems is derived from NS0. The Recombinant Human sFRP-1 (Histidine-tagged) Protein has been validated for the following applications: Bioactivity.
target :
sFRP-1
category :
Proteins and Enzymes
unit size :
25 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in NaH2PO4 and NaCl with BSA as a carrier protein.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
species :
Human
observed molecular weight :
35-40 kDa, reducing conditions
theoretical molecular weight :
33 kDa
gene symbol :
SFRP1
details of functionality :
Measured by its ability to inhibit proliferation of HeLa human cervical epithelial carcinoma cells. Ko, L. et al . (2002) Exp. Cell Res. 280 :280. The ED50 for this effect is 2.5-10 µg/mL.
endotoxin note :
<0.10 EU per 1 µg of the protein by the LAL method.
catalog number base :
1384-SF
accessionNumbers :
AAB70793
applications :
Bioactivity
source :
Mouse myeloma cell line, NS0-derived human sFRP-1 protein Ser32-Lys314 with a C-terminal 6-His tag
extended description :
A New and Improved rh sFRP-1 is Available! It has a lower endotoxin specification, ~3 fold better activity, and no tag!
2020 USD :
329
2021 USD :
329 USD
product details :
A New and Improved rh sFRP-1 is Available! It has a lower endotoxin specification, ~3 fold better activity, and no tag!
alt names :
FRP1, FRP-1FrzA, FRPSARP-2, FrzA, SARP-2, SARP2sFRP-1, Secreted apoptosis-related protein 2, secreted frizzled-related protein 1, sFRP1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.